乳腺癌患者血清中TGF的表达及意义  

Levels and significance of serum TGF in breast cancer patients

作　　者：鲁海文[1] 张超[2] 雷建灵[1] 

机构地区：[1]内蒙古医科大学附属人民医院,内蒙古呼和浩特010020 [2]内蒙古医科大学研究生学院

出　　处：《疾病监测与控制》2016年第4期277-278,共2页Journal of Diseases Monitor and Control

基　　金：内蒙古医科大学附属人民医院院内科研项目

摘　　要：目的研究乳腺癌患者血清中转化生长因子TGF的水平和意义。方法检测临床60例乳腺癌患者作为观察组及40例健康者作为对照组,比较两者血清中TGF的表达水平。结果患者血清中的TGF的水平明显高于对照组,其中III期的患者的血清因子水平也明显高于I期和II期的患者。而伴随着肿瘤的进展,瘤体的增长,TGF的水平也有所增长。以上结果经统计学分析皆具有统计学意义,即P﹤0.05。结论乳腺癌患者血清中的TGF的表达水平明显高于健康者的水平,在肿瘤的临床分级、分期及预后中具有临床意义。Objective To study the level and significance of transforming growth factor in serum of breast cancer patients. Methods 60 cases of breast cancer patients as observation group and 30 cases of healthy persons as control group, to compare the expression level of TGF in serum. Results The levels of TGF in serum of patients were significantly higher than those in control group, and the serum level of III was significantly higher than those of patients with I and II. And along with the progress of the tumor, the growth of the tumor, the level of TGF also increased. These results were statistically significant, P〈0.05. Conclusion The levels of TGF in serum of patients with breast cancer were significantly higher than those of healthy people, and the clinical significance of the clinical classification, staging and prognosis of patients with breast cancer.

关 键 词：乳腺癌 转化生长因子 

分 类 号：R73-2[医药卫生—肿瘤]