颅底软骨肉瘤的CT及MRI表现及临床病理学研究  

CT and MR features of cranial base chondrosarcoma and clinical pathological analysis

作　　者：景治涛[1] 崔启韬 李龙[1] 王鑫[1] 刘佳[1] 班允超[1] 

机构地区：[1]中国医科大学第一附属医院神经外科,沈阳110001

出　　处：《陕西医学杂志》2016年第4期457-459,共3页Shaanxi Medical Journal

基　　金：国家自然科学基金资助项目(81101917/H1618);辽宁省自然科学基金资助项目(2013021045)

摘　　要：目的:探讨颅底软骨肉瘤的影像学表现,诊断和病理学特点。方法:回顾性研究我院10年间进行显微手术治疗且病理证实为颅底软骨肉瘤的15例患者的临床资料,并对其进行细致分析。结果:颅底软骨肉瘤的主要临床表现为头痛、恶心或颅神经受压症状。CT示边界清楚的形态不规则肿物,边缘有钙化,其中高密度钙化多见,MRI表现为T1像多为等信号或低信号,T2像多为等信号或高信号,增强后出现环形强化或不均匀强化,11例病例诊断为高分化型软骨肉瘤,另4例为黏液型软骨肉瘤。结论 :颅底软骨肉瘤的临床及影像学表现缺乏特异性,常与颅底重要血管神经关系密切,病理诊断是其确诊的主要方法。Objective：Cranial base chondrosarcoma is comparatively rare in intracranial tumors with a lower incidence. This paper discusses the imaging findings,diagnosis, pathology. Methods：Retrospective study of nearly 10 years in our hospital 15 patients with pathological diagnosis for patients with cranial base chondrosarcomacases, who underwent surgical treatment, according to the imaging findings, pathological diagnosis and prognosis were analyzed carefully. Results：The main clinical manifestations were headache, nausea or cranial nerve compression symptoms. CT shows irregular mass, the boundary is clear and rim calcification, the mass center have high-density calcifications, T1WI shows hypointensity or isointensity signal, T2WI shows isointensity or hyperintensity signal, and uneven enhancement or circular strengthening. 11 cases were diagnosed well-differentiated chondrosarcoma, and the other 4 cases were myxoid chondrosarcoma. Conclusions：Cranial base chondrosarcoma is lack of the specific clinical manifestations and imaging feathers, and have close relationship between important nerve and vessel and tumor in cranial base, so most diagnosis depend on intraoperation findings and pathology.

关 键 词：颅底肿瘤/病理学 体层摄影术 X线计算机 磁共振成像 

分 类 号：R739.41[医药卫生—肿瘤]