老年人功能性便秘临床症状病理生理和治疗特殊性  

Clinical characteristics of functional constipation in the elderly：symptoms, pathophysiology and treatment

作　　者：樊文娟[1] 方秀才[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院消化内科,北京100730

出　　处：《中华老年医学杂志》2016年第4期448-451,共4页Chinese Journal of Geriatrics

摘　　要：老年功能性便秘患者临床症状更为特殊，表现为容易过度关注排便、排便费力明显、对便秘症状的感受重等。老年人肠道生理机能发生改变，肠神经元数量减少和退行性变，Cajal间质细胞数量的减少，以及肠道平滑肌收缩功能的减弱均参与了功能性便秘的发病。老年人基础疾病和合并用药情况复杂，在诊治中应注意药物相互作用和不良反应。The clinical symptoms of functional constipation in the elderly are more unique which represents as over concern about their bowel movement, excessive straining and worse feelings to the constipation. The intestinal physiological function declining with age, reductions of enteric neurons and interstitial cells of Cajal, neuronal degeneration and injured contractibility of intestinal smooth cells are enrolled in the pathogenesis of functional constipation. More attention should be paid to drug interactions and adverse effects in clinical practice due to more underlying disease and concomitant medication in the elderly.

关 键 词：便秘 胃肠活动 

分 类 号：R574.62[医药卫生—消化系统]