奥曲肽、垂体后叶素治疗肝硬化上消化道出血的疗效比较  

Comparison of Octreotide and Vasopressin in the Treatment of Cirrhosis Upper Gastrointestinal Hemorrhage

作　　者：杨甜[1] 

机构地区：[1]郑州大学附属洛阳中心医院消化内科,471000

出　　处：《中国继续医学教育》2016年第8期174-175,共2页China Continuing Medical Education

摘　　要：目的观察比较奥曲肽、垂体后叶素在肝硬化消化道出血临床治疗中的效果。方法选取2015年1月~2015年12月于我院接受治疗的90例肝硬化上消化道出血患者,根据治疗方式分为两组,各45例。奥曲肽组使用奥曲肽治疗,垂体后叶素组使用垂体后叶素治疗,比较两组疗效和不良反应。结果奥曲肽组总有效率和不良反应分别为93.33%、8.89%,垂体后叶素组分别为71.11%、33.33%,奥曲肽组临床疗效高于垂体后叶素组,不良反应少于垂体后叶素组,差异有统计学意义,P〈0.05。结论肝硬化上消化道出血使用奥曲肽治疗的效果较使用垂体后叶素佳,安全性更优。Objective To compare the effect of treating the cirrhosis upper gastrointestinal hemorrhage of applying octreotide and vasopress. Methods Selected 90 cases who suffer gastrointestinal bleeding in our hospital from January to December 2015,then divide them into two groups according to treatment ways. Each group had 45 patients. One group used the way of octreotide to treat, the other group used the way of pituitrin, then we can compare the efficacy and adverse reactions. Results The total efficiency and adverse reaction rates of octreotide group were 93.33%, 8.89%,but the vasopressin group were 71.11%, 33.33%, the clinical efficacy of the former was higher than the latter group, and the side effects was fewer than the latter, the difference had statistical significance, P0.05. Conclusion The treatment effect of the use of octreotide is better than the vasopressin in the treatment of upper gastrointestinal bleeding in cirrhosis and the security.

关 键 词：肝硬化上消化道出血 奥曲肽 垂体后叶素 

分 类 号：R573.2[医药卫生—消化系统]