TACE联合微波消融治疗原发性肝癌的效果分析  

Effectiveness analysis of TACE combined with percutaneous micro-wave coagulation therapy on primary liver cancer

作　　者：邓兴[1] 胡鸿[1] 游箭[1] 廖运国 文晓霞[1] 赵晓伟[1] 

机构地区：[1]川北医学院第二临床医学院.南充市中心医院影像科/介入放射科,四川南充637000

出　　处：《西部医学》2016年第4期524-527,共4页Medical Journal of West China

基　　金：四川省教育厅重点项目(11ZA188)

摘　　要：目的探讨经导管动脉化疗栓塞术（TACE）联合微波消融（PMCT）治疗原发性肝癌的临床价值。方法根据治疗方法的不同将2012年7月~2015年7月随访资料完整的75例中晚期肝癌患者分为观察组33例及对照组42例,对照组患者单纯采用TACE治疗,观察组则采用TACE联合微波消融治疗,观察手术前后两组血清甲胎蛋白（AFP）水平的变化,影像学检查（B超、CT、MRI）测量肝癌病灶直径等指标,随访1、3、6、12、24月和36月存活率。结果与对照组相比,观察组疗效明显提升、不良反应发生率显著下降、生存期延长,无出血、肿瘤破裂及肝功能衰竭等严重并发症发生。结论 TACE联合微波消融治疗原发性肝癌安全有效,并发症少,符合肿瘤微创、综合治疗理念,是中晚期肝癌患者较理想临床治疗方法。Objective To evaluate clinical value of transcatheter arterial chemoembolization（transcatheter arterial chemoembolization,TACE）and sequential combination microwave coagulation ablation（percutaneous micro-wave coagulation therapy,PMCT）on primary liver cancer.Methods 75 middle-late stage liver cancer patients were divided into observation group（n=33）and control group（n=42）.The control group was treated with conventional treatment.The observation group was treated with microwave ablation therapy and conventional treatment.The serum AFP protein and diameter of liver lesions（ultrasound,CT,MRI）were observed.The patients followed up for 1 month,3 months,6months,12 months,24months and 36 months of survival.Results Compared that of control group,the incidence of adverse reactions,survival duration,hemorrhage,rupture of the tumor and liver failure,and other serious complications of observation group reduced.Conclusion TACE combined with microwave coagulation ablation is safe and effective for treatment of primary liver cancer.

关 键 词：原发性肝癌 经导管动脉化疗栓塞术 微波消融 

分 类 号：R735.7[医药卫生—肿瘤]