白塞病胶囊内镜检查5例  

Capsule endoscopy for Behcet's disease-treatment: five cases reports

作　　者：黄勍[1] 王雪梅[1] 刘玉兰[1] 冯桂建[1] 尤鹏[1] 

机构地区：[1]北京大学人民医院消化科,北京100044

出　　处：《北京大学学报（医学版）》2016年第2期366-369,共4页Journal of Peking University:Health Sciences

摘　　要：白塞病（Behcet’s disease,BD）是一种原因不明的慢性多血管炎症性疾病,主要表现为反复口腔溃疡生殖器溃疡眼部损害及皮肤损害,并可累及血管、神经系统、消化道、关节、肺、肾、附睾等。白塞病累及消化道称为胃肠型白塞病,文献多称肠白塞病,全消化道均可受累。Behcet＇s disease（ BD） is a chronic vascular inflammatory disease of unknown causes. It is called intestinal BD,when digestive tract is involved. To investigate small bowel feature of intestinal BD,we now report 5 intestinal BD cases undergone capsule endoscopy from December,2010 to April,2014 in Peking University People＇s Hospital. General information,clinical feature and endoscopic feature were presented,and literatures were reviewed. There were 3 male and 2 female patients. Age range was from23 to 55 years old（ median age 40 years old）. Disease course was from 3 days to 28 years（ median course 9 years）. 4 patients were diagnosed as systemic BD,and the rest independent intestinal BD. 4systemic BD patients all presented as recurrent oral aphthous as initial symptom and had history of vulvar ulcer and skin lesion. They all had gastrointestinal symptoms,including retrosternal pain（ 2 cases）,hematochezia（ 3 cases）,diarrhea（ 3 cases） and abdominal pain（ 2 cases）. 1 patient had a history of fistula of ileocecal junction and underwent caecectomy. 5 patients all underwent whole digestive tract examination by endoscopy,including gastroscopy,colonoscopy and capsule endoscopy. Except of 1 normal result of colonoscopy,all endoscopy results revealed lesions. Capsule endoscopy results of all patients were abnormal. Types of small intestinal lesion were various,including ulceration,erosion,protrusion and vasculopathy. All digestive tract can be involved in BD patients. Capsule endoscopy can evaluate lesions throughout whole digestive tract,especially in small intestine. As a consequence,it is helpful to explain gastrointestinal symptom,increase early diagnostic rate. Intestinal BD（ IBD） mainly involves small bowel,and ileum is the major involved segment,not only limited in ileocecum. The updated perspective of IBD lesion distribution will contribute to differential diagnosis between IBD and Crohn＇s disease. This is the first time to report capsule endoscopic feature of BD patients in China

关 键 词：胶囊内窥镜检查 贝赫切特综合征 肠疾病 CROHN病 

分 类 号：R574[医药卫生—消化系统]