缺血性脑卒中危险因素的Logistic回归分析  

Logistic regression analysis of risk factors for ischemic cerebral stroke

作　　者：蒋宁[1] 林林[2] 张魁魁[1] 任宇坤 

机构地区：[1]黑龙江中医药大学附属第一医院心血管三病房,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第一医院放射科,黑龙江哈尔滨150040 [3]黑龙江中医药大学

出　　处：《心血管康复医学杂志》2016年第2期141-144,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的：探讨缺血性脑卒中（ICS）的危险因素对其发病的影响。方法：在哈尔滨市动力区〉40岁的12 241人中,选择既往已确诊ICS的患者350例为卒中组,另随机抽取该地区经查体的40岁以上非ICS人群350人为对照组。比较两组的ICS危险因素,利用多因素Logistic回归分析ICS发病的独立危险因素。结果：（1）除饮食口味（P〈0.01）外,两组的年龄、民族、文化程度、婚姻状况、职业等一般情况无明显差异（P〉0.05）;（2）多因素Logistic回归分析结果显示：两组的高血压病（OR=5.853,95%CI：3.188-10.673）、高脂血症（OR=5.601,95%CI：2.378-9.635）、颈动脉斑块（OR=4.963,95%CI：2.350-9.843）、心脏病（OR=4.568,95%CI：2.535-7.745）、高同型半胱氨酸血症（OR=4.076,95%CI：3.001-8.270）、明显超重（OR=3.421,95%CI：1.598-6.476）和脑血管病家族史（OR=3.065,95%CI：2.543-4.236）为ICS发病的独立危险因素（P均〈0.01）。根据OR值的大小,ICS的危险因素由大到小依次为：高血压病、高脂血症、颈动脉斑块、心脏病、高同型半胱氨酸血症、明显超重和脑血管病家族史。结论：除了传统的高血压病史、血脂异常和脑血管病家族史等危险因素以外,颈动脉斑块、心脏病、高同型半胱氨酸血症和明显超重也是脑卒中的重要危险因素。Objective：To explore influence of risk factors of ischemic cerebral stroke（ICS）on its onset.Methods：A total of 350 patients diagnosed as ICS were selected as stroke group among 12241〉40years people from Dongli district of Harbin city,another 350 〉40years non-ICS people,who were randomly selected from the same district,were enrolled as control group.ICS risk factors were compared between two groups,multi-factor Logistic regression analysis was used to analyze independent risk factors for ICS.Results：（1）There were no significant difference in age,nationality,education,marriage and professions between two groups except food taste（P〈0.01）;（2）Multifactor Logistic regression analysis indicated that hypertension（OR=5.853,95%CI：3.188-10.673）,hyperlipidemia（OR=5.601,95%CI：2.378- 9.635）,carotid artery plaque（OR=4.963,95%CI：2.350-9.843）,heart disease（OR=4.568,95%CI：2.535-7.745）,hyperhomocysteinemia（OR=4.076,95%CI：3.001-8.270）,apparent overweight（OR=3.421,95%CI：1.598-6.476）and family history of cerebrovascular diseases（OR=3.065,95%CI：2.543-4.236）were independent risk factors for ICS in both groups（P〈0.01all）.According to OR value from big to small,risk factors for ICS were hypertension,hyperlipidemia,carotid artery plaque,heart disease,hyperhomocysteinemia,apparent weight and family history of cerebrovascular diseases respectively.Conclusion：Besides traditional risk factors like hypertension,dyslipidemia and family history of cerebrovascular diseases,other risk factors such as carotid artery plaque,heart disease,family history of cerebrovascular disease and apparent overweight are also important risk factors for stroke.

关 键 词：卒中 脑缺血 危险因素 LOGISTIC模型 

分 类 号：R743.309[医药卫生—神经病学与精神病学]