血管内介入治疗周围型颅内动脉瘤17例  

Endovascular treatment of peripheral intracranial aneurysm:report of 17 patients

作　　者：谭华桥[1] 周育苗[2] 方淳 朱悦琦[3] 李永东[3] 李明华[3] 罗祖炎[4] 

机构地区：[1]同济大学附属同济医院介入放射科,上海200065 [2]浙江医院神经内科 [3]上海交通大学附属第六人民医院放射科 [4]浙江省人民医院放射科

出　　处：《介入放射学杂志》2016年第4期279-285,共7页Journal of Interventional Radiology

基　　金：上海市自然科学基金(12ZR1422500)

摘　　要：目的报道血管内介入治疗周围型颅内动脉瘤的效果和临床经验,探讨介入治疗策略。方法 2010年1月至2015年12月采用血管内介入术治疗17例周围型颅内动脉瘤（男7例,女10例,平均年龄52.1岁）,1例为偶然发现的血流相关性动脉瘤,16例为蛛网膜下腔出血,其中3例伴有脑实质内血肿,1例伴发脑室内出血,1例为偶然发现的其它部位动脉瘤破裂。动脉瘤位于小脑上动脉1例,脉络膜前动脉1例,大脑前动脉8例,小脑后下动脉4例,大脑后动脉3例。囊性动脉瘤9例,夹层动脉瘤7例,假性动脉瘤1例。所有动脉瘤均为小动脉瘤,2例梭形夹层动脉瘤缺乏明确瘤颈,15例为窄颈,其中5例体-颈比≤2,10例体-颈比〉2。结果血管内介入治疗技术成功率为100%。术后即刻,11例弹簧圈栓塞患者中7例囊状动脉瘤完全闭塞,1例囊状动脉瘤和2例夹层囊状动脉瘤不全闭塞,1例夹层囊状动脉瘤瘤颈残留;6例动脉瘤和载瘤动脉同时栓塞患者中5例完全闭塞,1例不全闭塞、载瘤动脉部分闭塞。术后3例出现神经功能缺损,其他患者无新发神经功能缺损。出院时改良Rankin量表（m RS）评分为0分14例,2分1例,4分2例。术后6~9个月血管造影和临床随访显示,11例弹簧圈栓塞患者中7例动脉瘤仍保持完全闭塞,3例不全闭塞,1例瘤颈残留患者复发;6例动脉瘤和载瘤动脉同时栓塞患者中5例动脉瘤仍保持完全闭塞,1例载瘤动脉再通。末次随访显示14例保持m RS评分0分,1例保持4分不变,2例m RS评分有明显改善。结论对于外科手术治疗较困难的周围型颅内动脉瘤,血管内介入治疗是一种安全有效的治疗方法。选择何种血管内介入治疗策略取决于动脉瘤部位、性质、形态、血管入路迂曲程度和载瘤动脉供血区功能重要程度。Objective To report the clinical results and the experience of endovascular treatment（EVT） for peripheral intracranial aneurysms（IAs） in 17 patients, and to discuss the interventional therapeutic strategy for peripheral IAs. Methods During the period from January 2010 to December 2015, a total of 17 patients with peripheral IAs were treated with EVT at authors＇ hospital. The patients included 7 males and 10 females with a mean age of 52.1 years. Peripheral IA was an accidental discovery as a blood flow-related aneurysm in one patient and was characterized by subarachnoid hemorrhage（SAH） in 16 patients, among whom concurrent intracerebral hematoma was found in 3, concurrent intraventricular hemorrhage was detected in one, and in another one the aneurysm was an accidental finding because of ruptured aneurysm located at other site. The peripheral IAs were located at superior cerebellar artery（n=1）, anterior choroidal artery（n=1）, anterior cerebral artery（n=8）, posterior inferior cerebellar artery（n=4） and posterior cerebral artery（n =3）. Pathologically, cystic aneurysm was seen in 9 patients, dissecting aneurysm was detected in 7 patients and false aneurysm was observed in one patient. All the 17 aneurysms were small in size; two fusiform dissecting aneurysms were lack of clear an eurysm neck; in 15 patients the aneurysm had a narrow neck, among which the dome-to-neck ratio was ≤2 in 5 and was 〉2 in 10. Results The technical success rate of EVT was 100%. Of the 11 patients who received spring coil embolization, complete occlusion of aneurysm was achieved immediately after the procedure in 7 patients with saccular aneurysms, incomplete occlusion of aneurysm was obtained in one patient with saccular aneurysm and two patients with dissecting saccular aneurysm, and residual neck was seen in one patient with dissecting saccular aneurysm. Of the 6patients whose aneurysm and parent artery were simultaneously embolized, complete occlusion of aneurysm was achieved in 5 and incomplete occ

关 键 词：周围型颅内动脉瘤 血管内介入治疗 蛛网膜下腔出血 

分 类 号：R743[医药卫生—神经病学与精神病学]