不同手术入路显微切除垂体瘤临床疗效观察  

Clinical study on resecting pituitary adenoma by microsurgery via two different surgical approaches

作　　者：王鹏[1] 许阳阳[1] 赵理乐[1] 

机构地区：[1]天津市西青医院神经外科,300380

出　　处：《淮海医药》2016年第3期279-281,共3页Journal of Huaihai Medicine

摘　　要：目的:观察经翼点开颅手术与经鼻蝶入路手术在切除垂体瘤治疗中的疗效,探讨治疗垂体瘤合理有效的手术方式。方法:选取2011年3月-2015年4月天津市西青医院收治的56例垂体瘤患者作为观察对象,30例经翼点开颅手术,26例经鼻蝶入路手术。结果:开颅组与鼻碟组,手术全切程度及术后并发症的发生比较,差异无统计学意义(P>0.05),而鼻碟组手术时间短、术中出血量少、住院时间短,2组比较差异有统计学意义(P<0.05)。结论:根据术者的经验及患者的具体情况制定垂体瘤个性化的治疗方案,经鼻碟入路手术方式具有优势。Objective： To compare the clinical effects of microsurgery for pituitary adenoma via transpterional approach and endonasal transsphenoidal approach and to understand the difference of the two approaches. Methods： 56 cases of patients were collected,who had undergone microsurgery in our hospital from March 2011 to April 2015. 30 of them were treated via transpterional approach while another 26 were treated via endonasal transsphenoidal approach. Results： The effects of the two groups were similar and the difference was not statistically significant（ P 0. 05） in terms of the tumor total removal degree and the complications after the operation.However,the transsphenoidal group had advantages over the transpterional group in terms of the duration of operation,bleeding volume and in hospital stays,and the difference was statistically significant（ P 0. 05）. Conclusion： Personalized scheme for treatment of pituitary adenoma should be formulated according to the experience of the operation performer and the patient＇s specific situation. The endonasal transsphenoidal approach has many advantages and is worth to be promoted.

关 键 词：垂体腺瘤 翼点入路 单鼻孔经蝶入路 显微外科手术 

分 类 号：R739.41[医药卫生—肿瘤]