盐酸舍曲林治疗脑卒中后抑郁障碍的临床疗效观察  

Sertraline hydrochloride treatment the clinical effect of the treatment of depression after stroke

作　　者：田国平[1] 

机构地区：[1]山西中医学院第三中医院,山西太原030006

出　　处：《基层医学论坛》2016年第12期1606-1607,共2页The Medical Forum

摘　　要：目的探讨盐酸舍曲林在脑卒中后抑郁障碍治疗中的临床效果。方法将我院收治的脑卒中后抑郁障碍患者70例,分别给予脑卒中常规药物治疗(对照组)与脑卒中常规药物联合舍曲林治疗(治疗组),观察2组治疗前后汉密尔顿抑郁量表(HAMD)评分、日常生活能力评定量表即Barthel指数(BI)评分、神经功能缺损(SSS)评分。结果 2组治疗8周后BI评分均增加,SSS评分均减少(P<0.05),治疗组较对照组的变化更显著(P<0.05)。治疗组治疗4周、8周后HAMD评分均较治疗前降低,与对照组相比差异有统计学意义(P<0.05)。结论舍曲林治疗脑卒中后抑郁障碍患者疗效确切,值得临床推广。Objective To investigate the effects of sertraline hydrochloride in the treatment of depressive disorder after stroke clinical effect. Methods Will be our hospital 70 cases of patients with depressive disorder after stroke respectively according to the conventional drug treatment（control group）and cerebral apoplexy cerebral apoplexy conventional drugs with sertraline therapy（treatment group）. Observe two groups before and after treatment the Hamilton depression scale（HAMD）score,daily life ability rating scale namely Barthel index（BI）score,nerve function defect score（SSS）.Results two groups8 weeks after treatment the BI score increased,SSS scores were reduced（P〈0.05）,the more significant changes in the treatment group than the control group（P〈0.05）.The treatment group after treatment of 4 weeks,8 weeks HAMD score was reduced,the difference was statistically significant compared with control subjects（P〈0.05）.Conclusion Sertraline treatment of brain death.

关 键 词：脑卒中 抑郁障碍 舍曲林 疗效观察 

分 类 号：R749.4[医药卫生—神经病学与精神病学]