衍生化技术在食品安全色谱分析中的应用  

The application of derivatization techniques in chromatographic analysis of food security

作　　者：罗夏琳 李攻科[1] 胡玉斐[1] 

机构地区：[1]中山大学化学与化学工程学院,广州510275

出　　处：《中国科学：化学》2016年第3期243-250,共8页SCIENTIA SINICA Chimica

基　　金：国家重大科学仪器设备开发专项(编号:2011YQ0301240901);国家自然科学基金(编号:21127008;91232703;21575167);广东省自然科学基金(编号:2015A030311020);广东省公益研究与能力建设专项(编号:2015A030401036)资助项目

摘　　要：近年来,食品安全问题已成为全球关注的焦点,色谱作为最常用的分析手段被广泛地应用于食品安全检测.然而,色谱方法在检测一些分子量小、极性高、挥发性差、热不稳定、生色基团少的分析物时会遇到检测响应值低、柱上保留时间短等问题,衍生化技术是克服这些问题的常用手段.本文主要介绍食品安全分析中常用衍生化试剂的使用选择和衍生化方法的建立以及衍生化技术在色谱检测食品中真菌毒素、非法添加剂、农兽药残留等物质的应用.In recent years, food safety issue has become one of the focuses of global concerns. Chromatography as the most common method has been applied to detecting harmful substances in food widely. However, chromatographic methods used in the detection of analytes with the characteristic of low molecular weight, high polarity, low volatility, thermal instability, less chromophore will encounter some problems such as low detection response and low retention time. While, derivatization is a common means to solve these problems. In this paper, we mainly introduced derivative reagents and derivatization methods in sample preparation. The applications of derivatization techniques in chromatographic analysis of mycotoxins, illegal additives, pesticide and veterinary drug residues, and so on in food samples were reviewed.

关 键 词：衍生化技术 色谱分析 食品安全 

分 类 号：O657.7[理学—分析化学] TS207.3[理学—化学]