不同体积的亚甲蓝检测Ⅰ期乳腺癌前哨淋巴结的对比研究  

Effect of different volumes of methyleneblue on detection of sentinel lymph node in one-stage breast cancer patients

作　　者：王宏[1] 陈伟荣[1] 林滔[1] 李柳丹 

机构地区：[1]珠海市妇幼保健院乳腺外科,广东珠海510001

出　　处：《岭南现代临床外科》2016年第2期149-152,共4页Lingnan Modern Clinics in Surgery

摘　　要：目的探讨不同体积的亚甲蓝注射液染色示踪法在Ⅰ期乳腺癌前哨淋巴结活检中的临床应用价值。方法回顾性分析自2010年1月至2015年6月,76例Ⅰ期乳腺癌病人,分低剂量组(0.2 mL),中剂量组(2 mL),高剂量组(4 mL)3组,使用1%亚甲蓝注射液为示踪剂,行术中前哨淋巴结活检术。结果 76例患者,成功施行75例前哨淋巴结活检术,检出率为98.7%,准确率为100%,阴性率为0。低剂量组并发症的发生率与另两组存在差异,其差异具有统计学意义。结论低剂量0.2 mL亚甲蓝示踪法在Ⅰ期乳腺癌前哨淋巴结中,准确性高,并发症少。Objective To investigate the clinical application of methylene blue staining with different volume in the sentinel lymph node biopsy of one-stage breast cancer. Methods From January2010 to June 2015, 76 patients with one-stage breast cancer were divided into low dose group（0.2 ml）,medium dose group（2 ml） and high dose group（4 ml）. 1% methylene blue was injected as tracer, and sentinel lymph node biopsy was done. Results Among 76 cases, 75 cases were detected sentinel lymph node biopsy. The detection rate was 98.7%, the accuracy rate was 100% and false negative rate was 0.There were significant differences in the incidence of complications in the low dose group and the other two groups. Conclusion As a tracer, low dose of 1% methyleneblu showed higher accuracy and less complications in detecting sentinel lymph nodes in one-stage breast cancer patients.

关 键 词：亚甲蓝 前哨淋巴结 乳腺癌 

分 类 号：R737.9[医药卫生—肿瘤]