动脉瘤样纤维组织细胞瘤1例及文献回顾  

A Case of Aneurysmal Fibrous Histiocytoma and Literature Review

作　　者：王琳[1] 邵莉梅[1] 刘静[1] 张广富[1] 

机构地区：[1]安徽淮北市人民医院皮肤科,安徽淮北235000

出　　处：《中国皮肤性病学杂志》2016年第5期501-503,共3页The Chinese Journal of Dermatovenereology

摘　　要：患者女,51岁。右前臂无痛性紫红色结节4年余。皮损组织病理示:角化过度,真皮内肿瘤组织主要由成纤维样细胞和组织样细胞组成,可见较多不规则的出血性裂隙与囊腔,裂隙及囊腔周边无内皮细胞。免疫组织化学染色示:肿瘤细胞波形蛋白(Vimentin)和CD68阳性,而结蛋白(Desmin),CD34及S-100均阴性。结合临床表现、组织病理改变和免疫组织化学染色,诊断为动脉瘤样纤维组织细胞瘤。A 51-year-old woman presented with a purple painless nodule on her right forearm for about 4 years. Histopathological examination of skin biopsy showed hyperkeratosis, tumor cells comprised of fibro-blast-like and histiocyte-like cells, irregular blood-filled spaces without endothelial cells. Immunohistochemically,the tumor cells were vimentin and CD65 positive, but negative for desmin, CD34 and S-100. It was diagnosed as aneurysmal fibrous histiocyloma according to clinical manifestation, histopathological and immunohistochemical features.

关 键 词：纤维组织细胞瘤 动脉瘤样 皮肤肿瘤 文献回顾 

分 类 号：R739.5[医药卫生—肿瘤]