头颈部鳞癌靶向治疗的研究进展  

Research progress in targeted therapy of head and neck squamous cell carcinomas

作　　者：尚丹丹[1] 陈鹏[2] 

机构地区：[1]解放军总医院口腔医学中心,北京100853 [2]解放军总医院口腔医颌面外科,北京100853

出　　处：《中华老年口腔医学杂志》2016年第2期120-124,共5页Chinese Journal of Geriatric Dentistry

摘　　要：头颈部肿瘤占全身恶性肿瘤的30%,多数为鳞状细胞癌,表现为多因子疾病,预后差。对于个性化治疗,较其他癌症,起步晚,发展慢,相对滞后。近年来随着对头颈部鳞癌研究的不断发展,在DNA、RNA和蛋白水平上的发病机制有了一定的认识。本文通过了解头颈部鳞癌的发病机制,对其靶向治疗的可能性进行分析作一综述。Head and neck cancer accounts for 30% of systemic cancer, mostly of most of which were squamous cell carcinoma. It is a multifactorial disease and its prognosis is poor. For personalized treatment, compared with other cancers, it starts started late and develops developed slowly,. Recent years, with the development of head and neck squamous cell, we have gained a certain amount of on DNA, RNA and protein levels in its pathogenesis. the pathogenesis of DNA, RNA and protein level has a certain understanding. By understanding the pathogenesis of head and neck squamous cell carcinoma, this paper reviews the possibilities of its targeted therapy.

关 键 词：鳞状细胞癌 多因子疾病 个性化治疗 

分 类 号：R739.91[医药卫生—肿瘤]