抑制在弱视研究中的进展  

The advances of suppression in research of amblyopia

作　　者：刘帅[1] 刘红[1] 

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼科,上海200031

出　　处：《中华眼科杂志》2016年第4期305-308,共4页Chinese Journal of Ophthalmology

基　　金：上海浦东卫生局重点协作项目（PW2012D-5）;上海市科委引导项目资助（134119a8900）

摘　　要：抑制是双眼竞争的结果,当健康人的抑制平衡点被打破时,就可导致弱视;抑制是弱视发病的重要机制之一.关于抑制的研究,早期提出了＂双阶段理论＂,并于基础研究角度确定了抑制存在的解剖定位;近年来不同学者设计了不同的模型来量化抑制程度,同时提出了新颖的去抑制的弱视治疗方法.笔者围绕抑制研究的新动态及去抑制的弱视治疗方法,做一综述.Suppression that is the result of interocular competition is an important machanism of amblyopia.The imbalance of suppression may lead the consequence to amblyopia.In the early study,researchers had raised the theory of Ⅱ.Quadratic Summation which had revealed the relationship of interocular interaction and suppression.In some basic researches, other studies had showed the most possible anatomic location of suppression.Recently, researchers found a new method to quantify the interocular suppression named the noise model.Further studies found a novel disinhibition therapy to treat amblyopia.We summarized the research advances in suppression and disinhibition treatment in amblyopia.

关 键 词：弱视 视觉 双眼 视知觉 感觉阈 光刺激 

分 类 号：R777.44[医药卫生—眼科]