原发性甲状腺恶性淋巴瘤的诊治及进展  

The diagnosis and treatment of primary thyroid lymphoma

作　　者：梁鹏[1] 王森[1] 陈康兵[2] 李茉[1] 刘洋[1] 李爽[1] 潘予韦 张轶西[3] 姜瑛[1] 

机构地区：[1]吉林大学第二医院甲状腺外科,长春130041 [2]吉林大学第二医院耳鼻喉外科,长春130041 [3]吉林大学第二医院肝胆胰外科,长春130041

出　　处：《中华耳鼻咽喉头颈外科杂志》2016年第4期313-316,共4页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

基　　金：吉林大学研究生创新基金（450060523297）

摘　　要：原发性甲状腺恶性淋巴瘤（primary thyroid lymphoma,PTL）指原发于甲状腺内淋巴组织的恶性肿瘤,其发病率占所有甲状腺恶性肿瘤的5％,占结外淋巴瘤的1％～3％,主要见50岁以上妇女,绝大部分为非霍奇金淋巴瘤,主要病理类型为黏膜相关淋巴组织淋巴瘤和弥漫性大B细胞淋巴瘤,且不同病理亚型其治疗方案也不同,因此明确其病理诊断特别重要,主要诊断手段有甲状腺超声检查、细针穿刺细胞学检查空芯针穿刺活组织检查及手术活检等,治疗方案有手术治疗、放射治疗、化学治疗、靶向治疗及联合治疗,手术主要作用明确诊断和解除气道压迫.PTL预后一般较好,本文讨论的核心是原发性甲状腺恶性淋巴瘤的诊断及治疗的进展.Primary thyroid lymphoma （PTL） refers to the malignant tumor of primary lymphoid tissue in the thyroid,accounting for approximately 5% of all thyroid malignancies and less than 3% of all extranodal lymphomas.PTL usually develops in females more than 50 years old.Most of PTL cases are nonHodgkin’s lymphomas.The major pathological subtypes are mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma.Treatment options for individual pathological subtypes are also different,so pathological diagnosis is very important.The main treatment options include surgical treatment,radiotherapy,chemotherapy,targeted therapy and combined therapy.The main aims of surgical treatment are to obtain a determined diagnosis and to relieve airway pressure,.The prognosis of PTL is generally excellent.

关 键 词：淋巴瘤 活组织检查 针吸 诊断 治疗 

分 类 号：R736.1[医药卫生—肿瘤]