中药异叶爬山虎抗氧化活性部位化学成分研究  

Chemical constituents of antioxidative extracts from Parthenocissus heterophylla( BI.) Merr.

作　　者：李嘉 张颖 何春欢 陈锋 姜平川 

机构地区：[1]广西壮族自治区中医药研究院化学所,南宁530022 [2]广西中药质量标准研究重点实验室,南宁530022

出　　处：《中南药学》2015年第12期1274-1276,共3页Central South Pharmacy

基　　金：广西壮族自治区科技厅项目(No.桂科重1355001-4-7);广西中药质量标准研究重点实验室课题(No.桂中重自201410)

摘　　要：目的对中药异叶爬山虎Parthenocissus heterophylla（BI.）Merr.抗氧化活性部位——乙酸乙酯萃取部位进行化学成分研究。方法采用硅胶、Sephadex LH-20柱色谱等方法进行分离纯化,根据理化性质及波谱数据鉴定化合物的结构。结果从异叶爬山虎乙酸乙酯萃取部位分离并鉴定了6个化合物,分别为豆甾-4-烯-3-酮（1）、胡萝卜苷（2）、芹菜素（3）、木犀草素（4）、槲皮素（5）、槲皮素3-O-β-D-葡萄糖苷（6）。结论化合物1-6为首次从该植物中分离得到。Objective To determine the chemical constituents of antioxidtive extracts from the whole plants of Parthenocissus heterophylla（BI.） Merr.. Methods Chemical constituents of antioxidtive extracts from the whole plant of Parthenocissus heterophylla（BI.） Merr. were isolated and purified by silica column chromatography and Sephadex LH-20 column chromatography. Their structures were elucidated by chemical and spectral analyses. Results Six compounds were obtained from ethyl acetate portion and were identified as stigmast-4-en-3-one（1）, daucosterol（2）, apigenin（3）, luteolin（4）, quercetein（5）, quercetein 3-O-β-D-glucopyranoside（6）. Conclusion Compound 1- 6were obtained from the plant for the first time.

关 键 词：爬山虎属 异叶爬山虎 化学成分 抗氧化活性 

分 类 号：R284[医药卫生—中药学]