18F—FDGPET／CT对不明原因腹腔积液的临床应用价值  

The clinical value of 18F- FDG PET/CT for the patients with ascites of unknown causes

作　　者：陆佩欧[1] 王文志[1] 李迎辞[1] 刘蕊[1] 胡玉民[1] 于丽娟[1] 

机构地区：[1]哈尔滨医科大学附属肿瘤医院PET/CT中心,哈尔滨150081

出　　处：《实用肿瘤学杂志》2016年第2期114-117,共4页Practical Oncology Journal

基　　金：黑龙江省卫生厅科研课题（2013077）

摘　　要：目的探讨18F—FDGPET／CT对不明原因腹腔积液的临床应用价值。方法分析106例以腹腔积液为首发症状、并行18F—FDGPET／CT以明确积液良恶性的资料，18F—FDGPET／CT判定结果采用两种方法：（1）PET／CT（定位）法：PET／CT诊断结果完全取决于腹膜上18F—FDG摄取情况，若是摄取增高则为恶性，同机CT只作为解剖定位；（2）PET／CT（形态）法：PET／CT结果需结合腹膜的CT形态学改变和PET上18F—FDG摄取情况进行综合分析。结果PET／CT（定位）鉴别腹腔积液良恶性的敏感性、特异性、准确性分别为90．2％、71．1％、82．1％，而PET／CT（形态）的敏感性、特异性、准确性分别为95．1％、93．3％、94．3％，原发灶检出率为85．2％。PET／CT（形态）的特异性和准确性高于PET／CT（定位）（P=0．002、P〈0．001），两者之间敏感性无统计学差别（P=0．250）。结论在腹腔积液良恶性鉴别方面，PET／CT（形态）比PET／CT（定位）更具有临床应用价值，18F—FDGPET／CT（形态）对恶性腹腔积液原发灶检出具有重要意义。Objective To assess the clinical value of lSF - FDG PET/CT for the patients with ascites of unknown causes. Methods A total of 106 patients with ascites undergoing lSF - FDG PET/CT examination was retrospectively studied and ＇SF -FDG PET/CT imaging was interpreted by two ways. （1）PET/CT（localization） ： Diagnostic results of PET/CT depended on the degree of lSF - FDG uptake in peritoneum with CT was trecoted as anatomical localization, and high lS F -FDG uptake in peritoneum was regarded as malignancy. （2）PET/CT（ mor- phology） ：Morphological changes of peritoneum on CT imaging and the degree of lS F- FDG uptake on PET ima- ging were simultaneously considered when interpreting the diagnostic results of PET/CT. Results In the differen- tial diagnosis of ascites of unknown cause, the sensitivity, specificity and accuracy of PET/CT（localization） were 90.2% ,71.1% and 82.1% ,respectively. These values of PET/CT（morphology） were 95.1% ,93.3% and 94. 3% ,and 85.2% of malignant ascites were found primary lesion. The specificity and accuracy of PET/CT（ mor- phology） were higher than those of PET/CT（localization） （P = 0. 002, P 〈 0. 001 ）. Statistical difference was not found in both sensitivities. Conclusion PET/CT（morphology） had higher clinical value than PET/CT（ localiza- tion） in the differential diagnosis of ascites with unknown cause, and had important significance in detecting pri- mary cause of malignant ascites.

关 键 词：腹腔积液 正电子发射型体层摄影术 体层摄影术 

分 类 号：R735.5[医药卫生—肿瘤]