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机构地区:[1]复旦大学附属肿瘤医院闵行分院肝胆胰中西医结合科,上海200240
出 处:《实用肿瘤学杂志》2016年第2期140-141,共2页Practical Oncology Journal
摘 要:眼眶转移癌发生比例较小,及早发现原发病灶非常关键。原发性胰腺癌眼眶转移更为罕见,机理尚不清楚。本文报告1例原发胰腺癌伴肝、左眼眼眶转移病例,为临床诊断提供了一定参考。患者经过颅骨和上腹部断层扫描、左眼眶占位摘除活检术,再结合术后病理及实验室检查结果拟诊。行单药健择化疗3周期,患者病症有所减轻。Orbital metastases rarely occur in the patients with cancer,especially from a primary pancreatic carcinoma. In patients presenting ophthalmologic symptoms such as local pain and periorbital edema, it is important to consider orbital metastatic disease. And it is also crucial to determine the site of the primary tumor for better treatments. The mechanism underlying the orbital metastasis from pancreatic carcinoma remains to be clari- fied. In this report,we describe the clinical characteristics of a case with orbital and hepatic metastases from pri- mary pancreatic carcinoma, providing a reference for clinical diagnosis. Computed tomography of the abdomen and left orbit, in combination with intraorbital biopsy, suggesting a primary pancreatic malignancy with metastatic disease. Surgical pathology and histopathological examination results confirmed the diagnosis. After single agent gemcitabine chemotherapy,the patient's symptoms relieved.
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