^(18)F-FDG PET-CT在确定乳腺癌术前诊断与分期中的临床价值  

Preoperative ^(18)F-FDG PET/CT in Detection and Staging in Breast Cancer

作　　者：卓小丽[1] 李诗运[1] 戴儒奇[1] 

机构地区：[1]海南省人民医院核医学科,海南海口570311

出　　处：《标记免疫分析与临床》2016年第4期442-445,469,共5页Labeled Immunoassays and Clinical Medicine

摘　　要：目的探讨18F-FDG PET-CT在确定乳腺癌术前诊断及分期中的临床价值。方法 2012年10月至2014年12月我院外科收治的均经病理检查确诊为乳腺癌患者中,有32例患者在术前进行了全面PET-CT检查,检查范围包含乳房原发病灶、区域淋巴结及周身脏器。最后将手术病理与PET-CT检查结果进行比较分析。结果 32例患者中,18F-FDG PETCT检查结果是:Ⅰ期是3例,Ⅱ期22例,Ⅲ期4例,Ⅳ期2例,良性肿块1例(最后病理证实为浸润性小叶癌)。Ⅰ期-Ⅱ期25例患者中PET-CT发现腋下淋巴结转移15例,同侧内乳淋巴结2例,锁骨上窝淋巴结1例。手术后病理或针吸活检病理提示:浸润性导管癌24例,浸润性小叶癌5例,导管内原位癌2例,高分化腺癌1例,腋下淋巴结转移14例,淋巴结转移正确率为93.3%(14/15)。结论18F-FDG PET-CT检查对于诊断乳腺癌具有较强的检测能力,尤其是在诊断腋窝淋巴结转移及远处转移中更具优势,对于乳腺癌术前诊断及分期具有较高的临床价值。Objective To evaluate ^18F-FDG PET / CT in preoperative detection and staging in breast cancer.Methods Samples in this study were operative breast cancer patients from October 2012 to December 2014 in our hospital. The diagnosis was confirmed by pathology. Thirty two patients underwent comprehensive PET / CT examination preoperatively,The examination covers breast primary tumor,regional lymph nodes and the whole body organs. PET / CT findings were compared with the results of surgical pathology. Results Out of 32 cases,PET / CT found,5cases of stage Ⅰ,22 cases of stage Ⅱ,3 cases of stage Ⅲ,1 of stage Ⅳ（ liver and bone metastasis）,1 case was benign. Out of 27 stage Ⅰ-Ⅱpatients,PET / CT found axillary lymph node metastasis in15 cases. The accuracy of PET / CT detecting lymph node metastasis was 93. 3%（ 14 /15）. Conclusion18F-FDG PET / CT plays a strong role in detecting breast cancer and localizing lymph node metastasis and other distant metastases. Use of PET / CT to detect axillary lymph node metastasis provides a highly sensitive clinical value for the diagnosis and staging breast cancer preoperatively.

关 键 词：乳腺癌 ^18F-FDG PET-CT 诊断 分期 

分 类 号：R737.9[医药卫生—肿瘤] R730.44[医药卫生—临床医学]