二次经皮穿刺球囊压迫治疗初次球囊术后复发性三叉神经痛  

Percutaneous Balloon Compression of Trigeminal Ganglion for Recurrent Trigeminal Neuralgia after Percutaneous Balloon Compression

作　　者：沈永锋[1] 王鼎[2] 杨定博 杜垣锋[2] 俞文华[2] 

机构地区：[1]杭州市肿瘤医院(杭州市第一人民医院吴山院区),310000 [2]南京医科大学附属杭州医院、杭州市第一人民医院,310000

出　　处：《医学研究杂志》2016年第4期69-72,共4页Journal of Medical Research

基　　金：浙江省科技计划项目(2013C33092);杭州市卫生科技计划项目(2013B13)

摘　　要：目的探讨二次经皮穿刺球囊压迫（percutaneous balloon compression，PBC）治疗初次PBC术后复发性三叉神经痛的临床疗效。方法回顾性分析了64例采用二次PBC治疗初次PBC术后复发性三叉神经痛患者的临床资料及疗效。结果术后疼痛即刻缓58例（90．6％），偶有疼痛但不需服药者3例（4．7％），疼痛未消失但服药可控制者2例（3．1％），较术前有所缓解但服药不能控制者1例（1．6％），整体有效率为95．3％。随访至今（2—63个月，平均随访时间2年以上），6例轻度复发，2例重度复发，2年复发率12．5％。术后患侧面部麻木60例（93．8％），咀嚼肌乏力36例（56．3％），口角疱疹29例（45．3％），无角膜溃疡、蛛网膜出血及其他严重并发症。结论二次PBC治疗初次PBC术后复发的三叉神经痛具有风险小、疗效好、复发率低的优点，是其较理想手术方案选择。Objective To evaluate the clinical effects of the patients with recurrent trigeminal neuralgia after percutaneous balloon compression treated with percutaneous balloon compression of trigeminal ganglion. Methods A total of 64 patients underwent a second PBC, and a retrospective study of the clinical data of these patients was performed. Results After PBC, pain relief was immediate.in 58 （90.6%） patients,and 3 （4.7%） patient had some pain and need no medication, 2 （3.1%）patients had some pain that could be controlled with medication. The total efficiency was 95.3%. With a mean length of follow - up of approximately 2 years after surgery, 6 cases had mild recurrence, 2 cases suffered severe recurrence. Postoperative morbidity included common side effects such as facial numbness in 60 （93.8%） patients, masseter muscle weakness in 36 （56.3%） patients, herpes in 29 （45.3%） patients. No corneal anesthesia, subaraehnoid hemorrhage or other serious surgical complications occurred in this study. Conclusion Repeated PBC is a minimally invasive, safe and low recurrent procedure which takes as an attractive choice for recurrent trigeminal neuralgia after PBC.

关 键 词：球囊压迫 三叉神经痛 复发 

分 类 号：R74[医药卫生—神经病学与精神病学]