内镜下钛夹定位在食管癌调强放疗靶区定位中的临床应用  

Clinical Application of Placing Titanium Clip in Target Localization of Esophageal Cancer Intensity Modulated Radiotherapy( IMRT) under The Endoscope

作　　者：刘申香[1] 袁昕[1] 魏本飞 王梅[1] 

机构地区：[1]扬州市第一人民医院临床肿瘤中心,225001

出　　处：《中国老年保健医学》2016年第2期88-91,共4页Chinese Journal of Geriatric Care

摘　　要：目的探讨内镜下放置钛夹在食管癌调强放疗靶区定位中的作用。方法回顾性分析了18例未行手术的食管癌患者,因其病变表浅,在CT上不能显示病灶范围,给调强放疗靶区勾画带来困难,故在放疗前使用内镜放置钛夹后,再勾画肿瘤靶区。结果经调强放疗后,17例患者完全缓解13例(其中8例达病理缓解),部分缓解4例,近期有效率100%;近期放射性副反应:放射性食管炎11例,放射性食管溃疡1例,放射性肺炎0例,放射性支气管炎3例,放射性皮肤黏膜损伤0例。结论内镜下放置钛夹非常有助于病变浅表的食管癌调强放疗勾画靶区,从而确保精确放疗顺利进行。Objectives Discuss effects of placing titanium clip in target localization of esophageal cancer IMRT under the endoscope. Methods Retrospectively analyze 17 cases of patients with esophageal cancer who have not been treated with surgeries because their esophageal lesions are too shallow to be shown on CT and it brings difficulties to delineate the target of IMRT. Therefore,as to delineate the target of tumor,we apply endoscope to place titanium clip. Results After using IMRT,there are 13 out of 17 patients get completely relieved（ including 8 patients get pathologic complete remission） and 4 get partial relief with recent 100% efficiency. Their recent radioactive side reactions： there are 11 patients get radiation esophagitis,1 gets radioactive esophageal ulcers,0gets radiation pneumonitis,3 get radioactive bronchitis and 0 gets radioactive skin mucous membrane injury. Conclusions Placing titanium clip under the endoscope is very helpful to delineate the target of esophageal cancer with superficial lesions IMRT and it make sure the precise radiotherapy goes with a swing.

关 键 词：食管癌 调强放疗 钛夹 

分 类 号：R735.1[医药卫生—肿瘤]