放射性^(131)Ⅰ治疗甲状腺癌术后的疗效评价  

Efficacy evaluation of radioactive ^(131)Ⅰ in the treatment of postoperative thyroid cancer

作　　者：陈飞[1] 何宗喜[1] 马宁帅[1] 李素平[1] 张涛[1] 

机构地区：[1]川北医学院附属医院核医学科,四川南充637000

出　　处：《中国现代医生》2016年第9期79-81,共3页China Modern Doctor

摘　　要：目的探讨放射性^(131)Ⅰ治疗用于甲状腺癌术后患者的临床疗效。方法回顾性分析2014年7月~2015年9月期间我院收治的100例甲状腺癌患者,根据治疗方案不同分为观察组和对照组各50例,两组患者均采用甲状腺全切术治疗,观察组术后进行放射性^(131)Ⅰ治疗,对照组则术后并不进行放射性^(131)Ⅰ治疗,对比两组患者的疗效及生存质量。结果观察组总有效率达到88.0%,显著高于对照组的72.0%,差异具有统计学意义(P<0.05);观察组患者的情绪功能、总体健康状况及疲倦评分均显著优于对照组(P<0.05),其他生存质量评分则差异无统计学意义(P>0.05)。结论甲状腺癌患者术后行放射性^(131)Ⅰ治疗,能够有效提高临床疗效,改善患者的生存质量,值得在临床上推广和应用。Objective To explore the clinical efficacy of radioactive iodine postoperative therapy for patients with thyroid cancer. Methods A total of 100 cases of thyroid cancer patients in our hospital from July 2014 to September 2015,were chosen as subjects, and according to different treatment options, they were divided into two groups, both with 50 patients. The patients in the two groups were treated with total thyroidectomy treatment. The observation group were received radioiodine therapy after surgery, and the control group were not received postoperative radioiodine therapy. Efficacy and quality of life of the two groups were compared. Results The total efficiency of the observation group was88.0%, significantly higher than 72.0% of the control group, and the difference was statistically significant（P〈0.05）. Emotional functioning, general health and fatigue scores in the observation group were significantly better than those of the control group（P〈0.05）, and there was no significant difference in comparing other quality of life scores（P〉0.05）. Conclusion Postoperative radioactive iodine treatment in patients with thyroid cancer, can effectively improve the clinical efficacy and patients＇ quality of life, and it is worthy of promotion and application in clinical practice.

关 键 词：甲状腺癌 放射性(131)Ⅰ 甲状腺全切术 生存质量 

分 类 号：R730.55[医药卫生—肿瘤] R736.1[医药卫生—临床医学]