浙江省三门县沿海地区人群血液和尿液中33种元素的生物监测(英文)  

Biomonitoring of 33 Elements in Blood and Urine Samples from Coastal Populations in Sanmen County of Zhejiang Province

作　　者：张素静[1] 骆如欣[1] 马栋[1] 卓先义[1] 

机构地区：[1]司法部司法鉴定科学技术研究所上海市法医学重点实验室,上海200063

出　　处：《法医学杂志》2016年第2期114-118,共5页Journal of Forensic Medicine

基　　金：supported by the Major Projects of Shanghai (15DZ1207500-2);the National Natural Science Foundation of China (81302613);Shanghai Technical Standards Special Foundation (13DZ0503001);the Council of Shanghai Key Laboratory of Forensic Medicine (14DZ2270800);the Grants from the National Key Technology R&D Program of the Ministry of Science and Technology of the People’s Republic of China (2012BAK16B02)

摘　　要：目的确立华东典型沿海地区浙江省三门县一般人群血液和尿液中33种元素(Ag、Al、As、Au、B、Ba、Be、Ca、Cd、Co、Cr、Cs、Cu、Fe、Ga、Hg、Li、Mg、Mn、Mo、Ni、Pb、Rb、Sb、Se、Sr、Th、Ti、Tl、U、V、Zn和Zr)的正常值参考范围。方法采用电感耦合等离子体质谱法检测272例血液样本和300例尿液样本中33种元素。采用SPSS 17.0软件对所得数据进行正态性检验,将所得数据与已有文献报道进行对比。结果建立了三门县一般人群血液和尿液中33种元素的正常值参考范围,其中Co、Cu、Mn和Sr等元素的正常值参考范围与其他报道相似,而As、Cd、Hg和Pb与其他研究报道存在差异,一般为高于其他报道,而血液中的Ba元素在各国文献报道之间差异较大。结论建立了三门县人群血液和尿液中33种元素的正常值参考范围,并成功应用于两例中毒案例的检测。Objective To determine the normal reference values of 33 elements, Ag, A1, As, Au, B, Ba, Be, Ca, Cd, Co, Cr, Cs, Cu, Fe, Ga, Hg, Li, Mg, Mn, Mo, Ni, Pb, Rb, Sb, Se, St, Th, Ti, T1, U, V, Zn and Zr, in the blood and urine samples from the general population in Sanmen County of Zhejiang province, a typical coastal area of eastern China. Methods The 33 elements in 272 blood and 300 urine samples were determined by inductively coupled plasma-mass spectrometry （ICP-MS）. The normality test of data was conducted using SPSS 17.0 Statistics. The data was compared with other reports. Results The normal reference values of the 33 elements in the blood and urine samples from the general population in Sanmen County were obtained, which of some elements were found to be similar with other reports, such as Co, Cu, Mn and Sr, while As, Cd, Hg and Pb were generally found to be higher than those previously reported. There was a wide variation between the reports from different countries in blood Ba. Conclusion The normal reference values of the 33 elements in the blood and urine samples from the general population in Sanmen County are established, and successfully applied to two poisoning cases.

关 键 词：法医毒理学 元素 电感耦合等离子体质谱法 血液 尿 沿海地区 

分 类 号：R446.112[医药卫生—诊断学]