目的分析溴鼠灵中毒大鼠尿液的代谢特征,揭示溴鼠灵干预对大鼠毒性作用的分子机制。方法通过构建大鼠溴鼠灵中毒模型,采用高效液相色谱-飞行时间质谱(high performance liquid chromatographytime of flight mass spectrometry,HPLC-TOF...
supported by the Major Projects of Shanghai (15DZ1207500-2);the National Natural Science Foundation of China (81302613);Shanghai Technical Standards Special Foundation (13DZ0503001);the Council of Shanghai Key Laboratory of Forensic Medicine (14DZ2270800);the Grants from the National Key Technology R&D Program of the Ministry of Science and Technology of the People’s Republic of China (2012BAK16B02)