宫颈电环切术在治疗CINⅡ～Ⅲ级中的临床应用  

Clinical application of loop electrosurgical excision procedure in the treatment of grade Ⅱ~Ⅲ CIN

作　　者：聂惠龙[1] 郭天棋[1] 

机构地区：[1]广东省珠海市妇幼保健院妇科肿瘤科,519000

出　　处：《中国实用医药》2016年第9期37-38,共2页China Practical Medicine

摘　　要：目的分析在Ⅱ、Ⅲ级宫颈上皮内瘤变（CIN）治疗中宫颈环形电切术（LEEP）的临床应用价值。方法 80例Ⅱ-Ⅲ级CIN患者作为观察对象,随机将其分为对照组和观察组,各40例。对照组接受宫颈冷刀锥切术（CKC）治疗,观察组接受LEEP治疗。对比两组手术时间、术中出血量、住院时间及宫颈愈合时间,并分析两组术后并发症的发生率。结果观察组术中出血量明显少于对照组,手术时间明显短于对照组,差异有统计学意义（P〈0.05）,而两组住院时间及宫颈愈合时间比较,差异无统计学意义（P〉0.05）。观察组术后并发症发生率明显低于对照组,差异有统计学意义（P〈0.05）。结论 LEEP可显著改善Ⅱ-Ⅲ级CIN的手术相关情况,并降低术后并发症发生率,值得临床推荐。Objective To analyze clinical application value of loop electrosurgical excision procedure（LEEP） in the treatment of grade Ⅱ-Ⅲ cervical intraepithelial neoplasia（CIN）. Methods A total of 80 patients of grade Ⅱ-Ⅲ CIN as observation subjects were randomly divided into control group and observation group, with 40 cases in each group. The control group received cold knife conization（CKC） for treatment, and the observation group received LEEP for treatment. Operation time, intraoperative bleeding volume, hospital stay time, and cervical healing time were compared between the two groups, and their incidences of postoperative complications were analyzed. Results The observation group had much lower intraoperative bleeding volume and shorter operation time than the control group, and the difference had statistical significance（P〈0.05）. There was no statistically significant difference of hospital stay time and cervical healing time between the two groups（P〉0.05）. The observation group had much lower incidence of postoperative complications than the control group, their difference had statistical significance（P〈0.05）. Conclusion LEEP can remarkably improve operation condition for grade Ⅱ-Ⅲ CIN, and reduce incidence of postoperative complications. This method is worth clinical promoting.

关 键 词：宫颈上皮内瘤变 宫颈环形电切术 宫颈冷刀锥切术 疗效 

分 类 号：R737.33[医药卫生—肿瘤]