单侧早期分化型甲状腺乳头状癌不同切除术式的临床对比研究  

Clinical comparative study of different kinds of resection in treatment of unilateral differentiated papillary thyroid carcinoma in the early stage

作　　者：田志龙[1] 王小凯[1] 高新宝[1] 奚海林[1] 冯苏[1] 贾高磊[1] 

机构地区：[1]徐州市中心医院,江苏徐州221009

出　　处：《腹腔镜外科杂志》2016年第4期259-262,共4页Journal of Laparoscopic Surgery

摘　　要：目的:探讨开放切除术及完全腔镜切除术治疗单侧早期分化型甲状腺乳头状癌的临床疗效及安全性。方法:选取2014年3月至2014年12月收治的100例单侧早期分化型甲状腺乳头状癌患者,随机分为A组(n=50)与B组(n=50),分别采用开放切除术及完全腔镜切除术。对比两组患者围手术期临床指标、术后美容满意度、远期复发率及并发症发生率等。结果:B组患者术中出血量、术后24 h疼痛评分均显著少于A组(P<0.05);A组患者手术时间显著短于B组(P<0.05);两组患者总淋巴结清扫数量、阳性淋巴结清扫数量差异无统计学意义(P>0.05);B组患者术后美容满意度显著高于A组(P<0.05);两组患者远期复发率、术后并发症发生率差异无统计学意义(P>0.05)。结论:相较传统开放手术,完全腔镜切除术治疗单侧早期分化型甲状腺乳头状癌可有效降低术中创伤程度,缓解术后疼痛,有助于提高术后美观性。Objective：To investigate the clinical effects and safety of open resection and totally endoscopic resection in treatment of unilateral differentiated papillary thyroid carcinoma in the early stage.Methods：One hundred patients with unilateral differentiated papillary thyroid carcinoma in the early stage were chosen in the period from Mar.2014 to Dec.2014 and randomly divided into Group A（ n = 50） with open resection and Group B（ n = 50） with totally endoscopic resection,and the perioperative clinical indicators,cosmetic satisfaction after operation,long-term recurrence rate and complication incidence of both groups were compared.Results：The intraoperative blood loss and pain score in 24 h after operation of Group B were significantly better than those of Group A（ P〈 0.05）.The operation time of Group A was significantly shorter than that of Group B（ P〉 0.05）.There was no significant difference in the number of total lymph node harvested and positive lymph node dissected between 2 groups（ P 〉0.05）.The cosmetic satisfaction after operation of Group B was significantly better than that of Group A（ P〈 0.05）.There was no significant difference in the long-term recurrence and postoperative complication incidence between 2 groups（ P 〉0.05）.Conclusions：Compared with open resection,totally endoscopic resection in treatment of unilateral differentiated papillary thyroid carcinoma in the early stage can efficiently reduce the trauma degree in operation,relieve the postoperative pain and be helpful in improving the postoperative cosmetic results.

关 键 词：癌 乳头状 甲状腺肿瘤 甲状腺切除术 内窥镜检查 疗效比较研究 

分 类 号：R736.1[医药卫生—肿瘤]