尤瑞克林治疗不同年龄段急性脑梗死患者效果分析  

Therapy effect analysis of Urinarykallid on acute cerebral infarction patients with different ages

作　　者：田强元[1] 齐鹏[1] 

机构地区：[1]山东省滨州市人民医院神经内科,256600

出　　处：《中国综合临床》2016年第4期353-355,共3页Clinical Medicine of China

摘　　要：目的探讨尤瑞克林对不同年龄段急性脑梗死患者的临床效果。方法将95例急性脑梗死患者根据年龄的不同分为高龄组（n=48）和中龄组（n=47）；两组均给予常规治疗结合尤瑞克林治疗，1个疗程（3周）后，比较两组疗效、治疗前后美国国立卫生院卒中量表（NIHSS）评分变化、治疗过程中不良反应发生情况。结果高龄组总有效率略低于中龄组，但差异无统计学意义（P=0．391）；两组患者治疗后NIHSS评分均较治疗前显著降低[高龄组：（9．81±2．37）、（6．79±0．82）分；中龄组：（9．75±2．46）、（3．04±0．58）分]，差异均有统计学意义（P=0．004，P=0．001），中龄组NIHSS评分降低的程度显著优于高龄组（P=0．000）；两组均无严重不良反应发生，治疗安全可靠。结论尤瑞克林对不同年龄段急性脑梗死患者均有显著疗效，且用药安全可靠，能显著改善患者NIHSS评分，年龄较低的患者改善程度优于高龄患者。Objective To investigate the effect of Urinarykallid for different ages patients with acute cerebral infarction cases. Methods Ninety-five cases with acute cerebral infarction were divided into high age group（n= 48） and middle age group （n = 47） . Patients in the two groups were both given the Urinarykallid therapy combined with routine treatment. After 1 courses of treatment（ 3 weeks） ,American National Institutes of Health Stroke Scale（NIHSS） were performed before and after the treatment. The adverse reactions occurred in the process of scoring were compared. Results The total effective rate in the high age group was 83.33%,lower than the middle age group（ 89. 36%） , but the difference was not statistically significant （P = 0. 391 ） . The NIHSS scores of patients in the two group after treatment were both significantly reduced compared with that in before treatment（high age grou： （9. 81±2. 37） vs. （6. 79±0. 82） ,middle age group： （9. 75±2. 46） vs. （3.04 ±0. 58;P=0. 004,P= 0. 001 ） . Meanwhile, the NIHSS in the middle age group decrease significantly than the high age group （P = 0. 000） . No obvious adverse reactions occurred in both two groups, the treatment was proved with safe and reliable. Conclusion Urinarykallid treatment is showed with better therapy effect on acute cerebral infarction patients with different age, and it is safety with improving patients NIHSS score level. Meanwhile, the better efficacy is showed in patients with lower age.

关 键 词：尤瑞克林 急性脑梗死 年龄 NIHSS评分 

分 类 号：R743.33[医药卫生—神经病学与精神病学]