脑梗死急性期患者血压变异性探究  

The study of blood pressure variability in patients with acute cerebral infarction

作　　者：黄国祥[1] 黄怀宇[1] 

机构地区：[1]南通大学第二附属医院神经内科,江苏南通226001

出　　处：《社区医学杂志》2016年第8期11-13,共3页Journal Of Community Medicine

摘　　要：目的探讨脑梗死急性期血压变异性并分析血压变异性与急性脑梗死早期神经功能恶化的相关性。方法选择2013年1月—2014年12月收治的急性脑梗死住院患者120例作为研究对象,参照TOAST分型分为大动脉粥样硬化组70例,小动脉梗死组30例和非动脉粥样硬化组20例。入院3 d内行动态血压监测,计算收缩压、舒张压标准差,并分析各组早期神经功能恶化发生情况和早期神经功能恶化患者血压变异系数。计量资料采用方差分析,两两比较采用LSD-t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果大动脉粥样硬化组和小动脉梗死组日间收缩压标准差(daytime systolic standard deviation,d SSD)、日间舒张压标准差(daytime diastolic standard deviation,d DSD)、夜间收缩压标准差(night systolic standard deviation,n SSD),夜间舒张压标准差(night diastolic standard deviation,n DSD)分别为(14.76±1.81)、(13.28±1.72)、(9.12±1.68)、(8.28±1.72)、(12.83±1.75)、(12.28±1.64)、(8.63±1.56)、(7.96±1.48)mm Hg(1 mm Hg=0.133k Pa),均高于非动脉粥样硬化组的(11.32±1.52)、(7.12±1.62)、(10.37±1.42)、(7.22±1.37)mm Hg,差异均有统计学意义(均P<0.05)。结论血压变异性与脑梗死病因分型密切相关,与早期神经功能恶化密切相关。Objective To explore the blood pressure variability in patients with acute cerebral infarction,and analyze the relationship between blood pressure variability with early neurological deterioration during acute cerebral infarction.Methods 120 cases of hospitalized patients with acute cerebral infarction from January 2013 to December 2014 were slelected.Based on the TOAST classification,the patients were divided into large artery atheroselerotic stroke （LAA） group （n=70）,small artery infaretion（SA）group （n=30）,and other non-atherosclerotic cerebral infarction（NAS）group（n=20）.All the patients were monitored for dynamic blood pressure in three days after hospitalize.Systolic and diastolic blood pressure standard deviation were calculated .The incidence of early neurological deterioration in each group,and blood pressure variation coefficient in patients with early neurological deterioration were analyzed.Measurement data Was processed by ANOVA,count data was processed by chi square test,P〈0.05 was considered statistically significant.Results The daytime systolic standard deviation （dSSD）,daytime diastolic standard deviation（dDSD）,night systolic standard deviation（nSSD） and night diastolic standard deviation（nDSD） in LAA group[（14.76 ± 1.81）,（9.12± 1.68）,（12.83± 1.75）,（8.63 ±.56）mm Hg（1 mm Hg=0. 133 kPa）]and SA group[（13.28 ±1.72）,（8.28 ± 1.72）,（12.28 ± 1.64）,（7.96 ± 1.48）mm Hg],were higher than those in NAS group [（11.32 ± 1.52）,（7.12± 1.62）,（10.37 ± 1.42）,（7.22 ± 1.37）mm Hg0,the differences were statistically significant（all P〈0.05）.Conclusion Blood pressure variability is closely related to the etiology of cerebral infarction and closely associated with early neurological deterioration.

关 键 词：脑梗死 血压变异性 早期神经功能恶化 

分 类 号：R743[医药卫生—神经病学与精神病学]