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机构地区:[1]无锡市第二人民医院普外科,江苏无锡214002
出 处:《职业与健康》2016年第7期1006-1008,共3页Occupation and Health
基 金:南京医科大学科技发展基金(2012NJMU251)
摘 要:目的探讨早期肠内营养支持疗法对老年胃底贲门癌患者术后的临床效果、可行性和安全性。方法将80例行胃底贲门癌手术的老年患者随机分为肠内营养组和肠外营养组,各40例,肠内营养组给予早期肠内营养支持疗法,而肠外营养组给予肠外营养支持疗法;观察并比较两组患者的术前和术后第7天营养状况、术后临床指标、并发症等。结果肠内营养组术后7天的血红蛋白、血清白蛋白、前清蛋白水平均明显高于肠外营养组(P<0.05);肠内营养组的肛门排气和排便时间短,营养费用低,与肠外营养组比较,差异有统计学意义(P<0.01);肠内营养组的腹胀、腹痛发生率为10.0%,明显低于肠外营养组的27.5%(P<0.05);而两组间的恶心呕吐、感染、肝肾功能损伤等并发症发生率比较,差异无统计学意义(P>0.05)。结论老年胃底贲门癌患者术后进行早期肠内营养支持疗法,可明显改善营养状况、加快机体恢复,减少并发症,具有有效、安全等特点。[Objective]To explore the clinical curative effect practicability and safety of early enteral nutrition support method in postoperative patients with gastric fundus and cardia carcinoma.[Methods]80 gastric fundus and cardia carcinoma patients undergoing operation were randomly divided into enteral nutrition group and parenteral nutrition group,40 cases in each group.The enteral nutrition group was given enteral nutrition support method,and the parenteral nutrition group was given parenteral nutrition support method.The nutritional state before operation and the seventh day after operation,clinical indexes after operation and complications were compared between the two groups.[Results]On the seventh day after operation,the levels of hemoglobin,serum albumin and prealbumin in the enteral nutrition group were significantly higher than those in the parenteral nutrition group(P〈.05).The exhaust time and defecation time in the enteral nutrition group were shorter than those in the parenteral nutrition group,while the nutrition cost in the enteral nutrition group was lower than that in the parenteral nutrition group,and the differences were statistically significant(P〈.01).The incidence rate of abdominal distension and stomachache in the enteral nutrition group(10.0%)was lower than that in the parenteral nutrition group(27.5%)significantly(P〈.05).There were no statistically significant differences in incidence rates of nausea and vomiting,infection and liver and kidney function injury between the two groups(P〈.05).[Conclusion]The early enteral nutrition support method can significantly improve the nutritional state in postoperative patients with gastric fundus and cardia carcinoma,speed up the recovery and reduce the complications,and it has the characteristics of effectiveness and safety.
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