吗替麦考酚酯在神经系统免疫性疾病中的临床应用进展  

Research progress on clinical application of mycophenolate mofetil in neuroimmune diseases

作　　者：黄艳露 邱伟[1] 

机构地区：[1]中山大学附属第三医院神经科,广州510630

出　　处：《新医学》2016年第4期210-213,共4页Journal of New Medicine

基　　金：国家自然科学基金面上项目(81471218)

摘　　要：吗替麦考酚酯(MMF)是一种具有免疫抑制作用的抗生素,已被广泛应用于器官移植与风湿性疾病,疗效肯定。近年来,MMF开始被应用于神经系统免疫性疾病,并取得了一定效果。该文就MMF在神经系统免疫性疾病中临床应用的最新进展作介绍,包括多发性硬化、视神经脊髓炎、重症肌无力、慢性炎症性脱髓鞘性多发性神经病、多灶性运动神经病、特发性炎症性肌病、神经系统结节病。Mycophenolate mofetil（ MMF） is a kind of immunosuppressive antibiotics,which has been widely applied in organ transplantation and treatment of rheumatoid diseases with high clinical efficacy. In recent years,MMF has been utilized to treat neuroimmune diseases and preliminary effect has been achieved.In this paper,recent progresses of clinical application of MMF in the management of neuroimmune diseases,such as multiple sclerosis,neuromyelitis optica,myasthenia gravis,chronic inflammatory demyelinating polyneuropathy,multifocal motor neuropathy,idiopathic inflammatory myopathy and neurosarcoidosis,were briefly summarized.

关 键 词：吗替麦考酚酯 神经系统免疫性疾病 不良反应 

分 类 号：R741[医药卫生—神经病学与精神病学]