腹主动脉转移淋巴结的调强放疗疗效分析  

Efficacy analysis of intensity modulated radiation therapy for abdominal aorta metastasis lymph nodes

作　　者：关永利[1] 赵瑞峰[1] 马骋远[1] 董志红[1] 张璋[1] 

机构地区：[1]晋城煤业集团总医院,山西晋城048006

出　　处：《临床医药实践》2016年第5期325-328,共4页Proceeding of Clinical Medicine

基　　金：山西省卫生厅基金项目(项目编号:201302005)

摘　　要：目的:分析三维适形放疗(3D-CRT)与调强适形放疗(IMRT)行腹主动脉旁转移淋巴结的照射剂量及近期疗效与不良反应。方法:分析2014年1月—2015年10月收治的18例腹主动脉旁淋巴结转移的患者,放疗前对每位患者分别作3D-CRT和IMRT两套治疗计划进行剂量对比分析,根据肿块大小及部位按时间顺序就近配对选择3D-CRT计划(三维组)或IMRT计划(调强组),采用6 MV加速器予以治疗,随访观察近期疗效及不良反应。结果:95%靶区覆盖剂量,调强组为(5 079.87±436.13)c Gy,三维组为(4 572.73±422.57)c Gy;95%靶区覆盖剂量,调强组为(5 123.27±442.78)c Gy,三维组为(4 665.90±339.16)c Gy;两组比较,差异有统计学意义(P<0.01)。两组近期疗效及不良反应发生率比较,差异无统计学意义。结论:IMRT技术在放疗剂量上较3D-CRT技术有一定程度提高,近期疗效及不良反应无明显差异。Objective： To analyze the the irradiation dose,the recent effect and adverse reactions of three dimensional conformal radiotherapy（ 3D- CRT） and intensity modulated conformal radiotherapy（ IMRT） on abdominal aorta. Methods： From January 2014 to October 2015,eighteen cases of para- aortic lymph node metastasis were analyzed. To compare and analyze the dose of 3D- CRT and IMRT for each patient before radiotherapy. According to the size and position of tumor,patients were divided into 3D- CRT plan group（ three- dimensional group） and IMRT plan group（ IMRT group）,were treated by 6 MV ac-celerator,to follow- up and observate the recent curative effect and adverse reactions. Results： 95% target coverage dose,group was（ 5 079. 87 ± 436. 13） cG y,three- dimensional group was（ 4 572. 73 ± 422. 57） cG y; 95% target coverage dose,group was（ 5 123. 27 ± 442. 78） cG y,three- dimensional group was（ 4 665. 90 ± 339. 16） cG y; there was have significant difference between the two groups（ P〈0. 01）. The recent curative effect and adverse reaction rate has no obvious difference between the two groups. Conclusion： IMRT technique on the radiation dose is 3D- CRT technology has a certain degree increase,no difference between the recent curative effect and adverse reactions.

关 键 词：腹主动脉旁淋巴结 调强放疗 疗效 不良反应 

分 类 号：R737.33[医药卫生—肿瘤]