577nm阈下微脉冲激光治疗视网膜分支静脉阻塞继发黄斑水肿疗效观察  

The efficacy of subthreshold micropulse 577nm laser for macular edema secondary to branch retinal vein occlusion

作　　者：郑瑜[1] 沙翔垠[1] 宋莉[1] 

机构地区：[1]广州医科大学附属第二医院眼科,广州510260

出　　处：《中国实用眼科杂志》2016年第5期439-442,共4页Chinese Journal of Practical Ophthalmology

基　　金：广东省中医药局资助项目（20141178）

摘　　要：目的 观察577 nm阈下微脉冲激光光凝治疗视网膜分支静脉阻塞（BRVO）继发黄斑水肿的疗效.方法 回顾性系列病例研究.将2013年3月至2014年3月在广州医科大学附属第二医院眼科病程≤3个月确诊为BRVO继发黄斑水肿的患者15例15只眼,给予黄斑水肿区域行577 nm阈下微脉冲激光光凝治疗,光凝后随访9～12个月,对比治疗前后最佳矫正视力（BCVA）,黄斑中心视网膜厚度（CMT）及眼底荧光血管造影（FFA）改变.结果 治疗前BCVA为：0.34±0.18,治疗后3、6、9个月BCVA分别为0.55±0.15,0.67±0.12,0.68±.0.13,治疗前与治疗后各时间点比较差异有统计学意义（P＜0.05）.治疗前CMT为：（451.53±147.38） μm,治疗后3、6、9个月CMT为（284.33±96.91）、（228.73±72.78）、（213.40±63.24） μm,治疗前与治疗后各时间点CMT比较差异有统计学意义（P＜0.05）.结论 577 nm阈下微脉冲激光治疗BRVO继发黄斑水肿,可以有效改善或稳定视力,减轻黄斑水肿,且损伤小,可以重复治疗,是安全有效的治疗手段.Objective To investigate the efficacy of subthreshold micropulse 577nm laser for macular edema secondary to branch retinal vein occlusion （BRVO）.Methods A retrospective case-series study.Fifteen patients （15 eyes） of macular edema secondary to BRVO,whose course of disease was not more than three months,were given subthreshold micropulse 577nm laser.The best corrected visual acuity （BCVA）,central macular thickness （CMT） and fundus fluoresceine angiography （FFA） were analyzed before and after treatment during the 6-9 months follow-up visit.Results Preoperative BCVA was （0.34±0.18）,while postoperative BCVA were （0.55±0.15）,（0.67±0.12）,（0.68±0.13）,respectively in 3 months,6 months and 9 months.Statistically differences were found （P 〈0.05）.The preoperative CMT was （451.53±147.38）μm,while that of post-treatment in 3 months,6 months and 9 months were （284.33±96.91）μm,（228.73±72.78）μm,（213.40±63.24）μm,respectively.There were statistically differences （P 〈0.05）.Conclusions The treatment of subthreshold micropulse 577nm laser for macular edema secondary to BRVO can effectively improve the visual acuity or make it stable and lighten the macular edema.This method is less damage,repeatable,safe and effective.

关 键 词：视网膜分支静脉阻塞 黄斑水肿 微脉冲激光 

分 类 号：R774.1[医药卫生—眼科]