脑桥出血早期患者脑皮质结构变化的磁共振研究  

Magnetic resonance imaging of structural change in the cerebral cortex for early pons hemorrhage patients

作　　者：莫本成[1] 张自力[1] 敖锋[1] 刘振华[1] 杨凡[1] 李华菊[1] 

机构地区：[1]湖北医药学院附属人民医院磁共振室,湖北442000

出　　处：《脑与神经疾病杂志》2016年第5期315-318,共4页Journal of Brain and Nervous Diseases

摘　　要：目的探讨脑桥出血早期患者脑皮质结构变化,并分析与感觉运动功能损伤的相关性。方法选择2014年5月至2015年3月本院接诊的16例脑桥出血患者进行研究将其作为观察组,选取同期16例健康者作为对照组。观察组患者入院后给予结构磁共振(MRI)检测,通过基于体素形态学方法对MRI的结构数据进行分析,比较两组患者大脑灰质体积区域的改变。并通过相关性分析患者脑皮质结构的改变与运动感觉功能的关系。结果两组患者在年龄与性别方面差异无统计学意义(P>0.05);观察组的轻触觉评分、针刺觉评分以及运动评分均低于对照组,两组比较差异具有统计学意义(P<0.001);基于体素形态学方法分析结果显示,观察组的双侧初级感觉中心、初级运动中心及其辅助运动区发生了灰质体积减小的现象(P<0.05);观察组结构异常区域萎缩发生程度经相关分析与轻触觉评分、针刺觉评分以及运动评分无相关性(P>0.05)。结论脑桥出血早期患者初级感觉中心、初级运动中心及其辅助运动区发生了灰质萎缩,但是萎缩程度与患者轻触觉评分、针刺觉评分以及运动评分无关。Objective To evaluate the structural change in the cerebral cortex for early pons hemorrhage patientsandanalysissensorymotorfunctionimpairement.Methods 16patientswithpontinehemorrhagefromMay 2014 to March 2015 in our hospital were researched as observer group.Select the same period 16 cases of healthy people as a control group.After admission, observation group structure of magnetic resonance detection, analysis the method based voxel morphology structure of magnetic resonance data,compare two groups of patients with brain gray matter volume area change, And through the correlation analysis of structural changes in the patients with cerebral cortex and the relationship between the sensorimotor function.Results Two groups of patients with no significant difference in age and sex （ P〉0.05）; Observation group the light touch of a grade, acupuncture and sports scores were lower than the control group, there was statistically significant （ P〈0.001）;Method based on voxel morphology analysis, according to the results of observation group of bilateral primary sensory center, primary motor and its auxiliary motor area occurred the phenomenon of gray matter volume （ P〈0.05 ）; Observation group structure abnormal occurrence area shrink by correlation analysis and light touch a grade, acupuncture and sports scores no correlation （P〉0.05）.Conclusion Pons hemorrhage in patients with early primary feeling center, the primary sports center and gray matter atrophy of the supplementary motor area,but there is no relationship of light touch a grade, acupuncture, and sports scores.

关 键 词：脑桥出血 脑皮质 磁共振 

分 类 号：R743.34[医药卫生—神经病学与精神病学]