胰腺癌病人小肠细菌过度生长检测及临床意义  

OVERGROWTH OF BACTERIA IN SMALL INTESTINE OF PATIENTS WITH PANCREATIC CANCER:ITS DETECTION AND CLINICAL SIGNIFICANCE

作　　者：王静[1] 曾跃[2] 马晓莹[1] 张东生[3] 许琳[1] 

机构地区：[1]青岛大学医学院附属青岛市市立医院消化内科,山东青岛266071 [2]贵州省安顺市人民医院消化内科 [3]青岛大学医学院附属青岛市市立医院肝胆外科

出　　处：《齐鲁医学杂志》2016年第2期133-134,137,共3页Medical Journal of Qilu

基　　金：青岛市科技局立项课题(13-1-3-14-nsh);青岛市医疗卫生优秀人才培养项目

摘　　要：目的探讨胰腺癌病人小肠细菌过度生长(SIBO)情况及其临床意义。方法通过葡萄糖氢呼气试验检测30例胰腺癌病人及30例健康志愿者SIBO情况。结果胰腺癌组和对照组SIBO阳性率分别为56.67%和3.33%,胰腺癌组SIBO阳性率显著高于对照组(χ2=20.32,P<0.05)。结论胰腺癌病人较健康人更容易发生SIBO,检测病人SIBO情况可以指导临床治疗,从而缓解病人部分临床症状,改善生活质量。Objective To investigate the overgrowth of bacteria in small intestinal of patients with pancreatic cancer （PC）. Methods Glucose hydrogen breath test was used to detect the overgrowth of bacteria in small intestine of 30 patients with PC and 30 healthy volunteers. Results The positive rate of overgrowth of bacteria in small intestine was 56.67% in the patients, and that in the healthy controls was 3.33%, the difference being significant （X2 =20.32,P〈0.05）. Conclusion Overgrowth of bacteria in small intestine is more likely to happen in patients with pancreatic cancer than in healthy individual, detection of this condition can be used to guide clinical treatment for relieving some clinical symptoms and improving qualityof life.

关 键 词：小肠 细菌 胰腺肿瘤 葡萄糖氢呼气试验 

分 类 号：R735.9[医药卫生—肿瘤]