胃肠道恶性肿瘤患者营养状况评价及影响因素分析  

Study on nutritional status and its influence in patients with gastrointestinal malignant tumor

作　　者：陈满宇[1] 吕龙[1] 何秋山[1] 

机构地区：[1]襄阳市中心医院,湖北文理学院附属医院,湖北襄阳441021

出　　处：《东南大学学报（医学版）》2016年第2期208-211,共4页Journal of Southeast University(Medical Science Edition)

基　　金：湖北省卫生计生委青年科技人才项目(QJX2012-40)

摘　　要：目的:探讨胃肠道恶性肿瘤患者的营养状况,并分析胃肠道恶性肿瘤患者营养不良的影响因素,为患者营养支持治疗提供依据。方法:选择200例胃肠道恶性肿瘤患者作为研究对象,应用简易营养评估法(mini nutritional assessment,MNA)对患者的营养状况进行综合评价,采用多因素Logistic回归分析筛选可能影响胃肠道恶性肿瘤患者营养状况的相关因素。结果:200例胃肠道恶性肿瘤患者的MNA均分为(20.10±3.59)分;其中营养状况正常(MNA≥24)者46例(23.0%),潜在营养不良(17≤MNA≤23.5)者99例(49.5%),营养不良(MNA<17)者55例(27.5%)。多因素Logistic回归分析结果显示:年龄(OR=2.213)、罹患感染性疾病(OR=2.905)、总蛋白缺乏(OR=8.907)、低蛋白血症(OR=7.152)、未服用营养粉/蛋白粉(OR=0.443)是胃肠道恶性肿瘤患者营养不良发生的独立危险因素。结论:胃肠道恶性肿瘤患者营养不良的现患率较高,针对胃肠道恶性肿瘤患者营养不良的相关影响因素制定有针对性的临床干预措施可以有效地降低患者营养不良的发生。Objective： To evaluate nutritional status and its influence in patients with gastrointestinal malignant tumor , and to provide the basis for nutritional support for patients .Methods：Two hundred cases of gastrointestinal malignant tumor were selected as research object and nutritional status were assessed by mini nutritional assessment （ MNA） .Multiple-factor Logistic regression analysis was used to screen the related factors affecting the nutritional status of patients with gastrointestinal cancer .Results： The patieuts mean MNA score was （20.10 ＆#177;3.59） points and 46 cases （23.0%）nutritional status were normal（MNA≥24）,99 cases（49.5%）were potential malnutrition （17≤MNA≤23.5）,55 cases（27.5%）were malnutrition（MNA〈17）.Multiple-factor Logistic regression analysis＆amp;nbsp;showed that age（OR=2.213）, suffering from infectious diseases（OR=2.905）, total protein deficiency（OR=8.907）, hypoalbuminemia （ OR =7.152 ）, not taking nutrition powder/protein powder （ OR =0.443 ） were independent risk factors for gastrointestinal cancer patients malnutrition occurs . Conclusion： The current prevalence rate of malnutrition is high in patients with gastrointestinal malignant tumor .The targeted clinical interventions for the related factors can effectively reduce the incidence of malnourished patients .

关 键 词：胃肠道恶性肿瘤 营养状况 评价 影响因素 

分 类 号：R735.3[医药卫生—肿瘤]