TLD在肿瘤放疗中剂量测量基本特性研究  

Elementary properties of thermoluminescent dosimeter in dosimetry for tumor radiotherapy

作　　者：江芬芬[1] 王培[2] 康盛伟[2] 祁国海[2] 肖明勇[2] 黎杰[2] 

机构地区：[1]江西省妇幼保健院肿瘤科放疗室,南昌330006 [2]四川省肿瘤医院放疗科,成都610041

出　　处：《中华放射肿瘤学杂志》2016年第5期496-499,共4页Chinese Journal of Radiation Oncology

基　　金：四川省卫生厅课题（110258）

摘　　要：目的研究LiF（Mg、Cu、P）TLD在肿瘤放疗中测量剂量的基本特性，为临床放疗热释光剂量测量提供可靠依据。方法应用^60Coγ射线和6MVX射线进行LiF热释光片的分散性、重复性、剂量响应等实验。根据临床放疗需要研究热释光计在肿瘤测量中随能量、剂量（50～600cGy）、照射剂量率（50～600MU／min）和加速器机架角度（0°～±90°）变化影响，分别求出校正因子。结果LiF热释光计重复性和分散性的误差控制在±3％以内，一定剂量范围照射下的读出数值与照射剂量呈线性关系。用6MVX射线照射，剂量率为300MU／min，入射角度为0°，得到的读数值的相对偏差最小，为0．3％。结论LiF热释光计具有重复性好、分散性小、稳定性高、线性相关性强等基本特性，符合国际推荐标准．可应用于肿瘤放疗中剂量的测定。Objective To explore the elementary properties of LiF （Mg, Cu, and P ） thermoluminescent dosimeter （TLD） in dosimetry for tumor radiotherapy, and to provide a reliable basis for thermoluminescent dosimetry in clinical radiotherapy. Methods ^60Coγ-ray and 6 MV X-ray were used for evaluation of the dispersion, repeatability, and dose response of LiF TLD. To meet the requirement of clinical radiotherapy, the effects of energy, dose （50-600 cGy）, radiation dose rate （50-600 MU/min）, and the angle of incidence for accelerator gantry （0°～±90°） on TLD were determined and the respective correction factors were calculated. Results The errors of repeatability and dispersion of TLD were less than ±3%. There was a linear relationship between readout and irradiation dose within a certain range of irradiation dose. The minimal relative deviation of 0. 3% was obtained when 6 MV X-ray was used with a dose rate of 300 MU/min and an angle of incidence of 0~. Conclusions LiF TLD shows excellent repeatability, low dispersion, high stability, and strong linear correlation. It meets the international criteria and can be used for dose measurement in tumor radiotherapy.

关 键 词：热释光剂量计 放射疗法 剂量学 基本特性 相对偏差 

分 类 号：R730.55[医药卫生—肿瘤]