脑功能影像技术在发育与行为儿科学中的应用  

Application of brain functional imaging technology for developmental and behavioral pediatrics

作　　者：马骏[1] 张安易 金星明[1] 

机构地区：[1]上海交通大学医学院附属上海儿童医学中心发育行为儿科,中国上海200127

出　　处：《教育生物学杂志》2016年第1期1-6,共6页Journal of Bio-education

基　　金：上海市科委2014年医学引导类基金(14411969200)

摘　　要：现代脑功能影像技术的发展,将发育与行为儿科学带入一个新时代。脑功能影像技术不仅能从脑激活、脑连接及大脑整体系统障碍的角度揭示发育与行为障碍的大脑功能缺陷机制,还有望构建一体化的脑认知神经障碍模型,全面阐释发育与行为障碍的脑病理机制,并从根本上把握疾病产生的异常神经通路,为行为干预及药物治疗找到靶点。以正常儿童大脑发育、多动症、孤独症、遗尿症和抽动症为例,阐述脑功能影像学技术在发育与行为儿科学研究应用中的进展。Developmental and behavioral pediatrics is promoted to a new era by the development of modern brain functional imaging technologies.Brain functional imaging technologies are not only capable of discovering the exact mechanisms of brain deficits in developmental and behavioral disorders from brain activations,brain connections,and the whole brain system,but also helping constructing an integrated model of cognitive neural disorders.This may point towards the aberrant neural pathways which caused a variety of developmental and behavioral disorders.It may be useful to explore the targets for drug or other treatments.Take the brain development of typically developing children,children with attention deficit hyperactivity disorder,autism,enuresis,and tics for examples,in this article we formulate the application progress of modern brain functional imaging technologies on developmental and behavioral pediatrics.

关 键 词：脑功能影像技术 功能性磁共振成像 发育与行为儿科学 脑发育障碍 行为障碍 

分 类 号：R749.94[医药卫生—神经病学与精神病学]