Self-assembling peptide nanofibrous hydrogel as a promising strategy in nerve repair after traumatic injury in the nervous system  

作　　者：Na Zhang Liumin He Wutian Wu 

机构地区：[1]Guangdong-Hongkong-Macao Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong Province, China [2]School of Biomedical Science, LKS Faculty of Medicine, the University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China [3]State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China [4]Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong Province, China

出　　处：《Neural Regeneration Research》2016年第5期717-718,共2页中国神经再生研究（英文版）

基　　金：supported by National Basic Research Program of China(973 Program,2014CB542205);Hong Kong RGC grant;Hong Kong Health and Medical Research Fund;foundation for Distinguished Young Talents in Higher Education of Guangdong(Yq2013023);the Leading Talents of Guangdong Province(87014002)

摘　　要：Following injury in central nervous system（CNS）,there are pathological changes in the injured region,which include neuronal death,axonal damage and demyelination,inflammatory response and activation of glial cells.The proliferation of a large number of astrocytes results in the formation of glial scar.Following injury in central nervous system（CNS）,there are pathological changes in the injured region,which include neuronal death,axonal damage and demyelination,inflammatory response and activation of glial cells.The proliferation of a large number of astrocytes results in the formation of glial scar.

关 键 词：NSCs Self-assembling peptide nanofibrous hydrogel as a promising strategy in nerve repair after traumatic injury in the nervous system RGD 

分 类 号：R741[医药卫生—神经病学与精神病学]