西沙必利联合胆石通胶囊治疗老年人功能性便秘临床效果观察  

The clinical effect of Cisapride combined with Danshitong capsule in the treatment of senile functional constipation

作　　者：彭景拾 

机构地区：[1]光山县人民医院内科,河南465450

出　　处：《中国临床新医学》2016年第5期414-417,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的探讨西沙必利联合胆石通胶囊治疗老年人功能性便秘的效果。方法选择老年功能性便秘患者120例,采用随机数字表法分为观察组和对照组,每组60例。对照组给予西沙必利治疗,观察组西沙必利联合胆石通胶囊治疗,均治疗2周后观察疗效。结果观察组直肠最低敏感量(164.52±10.79)ml,最大耐受量(231.64±23.61)ml;对照组直肠最低敏感量(180.67±18.57)ml,最大耐受量(252.86±31.46)ml,组间比较差异有统计学意义(P<0.05)。观察组治疗后每周排便(3.87±1.22)次,大便困难积分(1.67±0.16)分,大便性状积分(2.72±0.89)分;对照组治疗后每周排便(3.11±0.74)次,大便困难积分(2.13±0.58)分,大便性状积分(1.94±0.48)分,组间比较差异有统计学意义(P<0.05)。结论西沙必利联合胆石通胶囊治疗老年人功能性便秘可以有效改善肛门直肠感觉,促进肛门直肠协调收缩,改善排便情况和症状,值得在临床推广使用。Objective To explore the effect of cisapride combined with Danshitong capsule in the treatment of senile functional constipation. Methods One hundred and twenty patients with senile functional constipation,were randomly divided into the observation group and the control group,with 60 cases in each group. The control group received cisapride for treatment and the observation group was treated with cisapride in combination with Danshitong capsules. The curative effect was compared between the two groups 2 weeks after the treatment. Results There were significant differences in the minimum amount sensitive to rectum（ 164. 52 ± 10. 79） ml vs（ 180. 67 ± 18. 57） ml,in maximum tolerance（ 231. 64 ± 23. 61） ml vs（ 252. 86 ± 31. 46） ml between the observevation group and the control group（ P〈0. 05）. The times of bowel movements per week and scores of stool consistency in the observation group were significantly more than those in the control group [（ 3. 87 ± 1. 22） vs（ 3. 11 ± 0. 74） and（ 2. 72 ± 0. 89） vs（ 1. 94 ± 0. 48） ]. The score of dyschesia in the observation group（ 1. 67 ± 0. 16） was significantly less than that in the control group（ 2. 13 ± 0. 58）,（ P〈0. 05）. Conclusion Cisapride in combination with Danshitong capsule can effectively improve the anal sensation,promote the anorectal coordinating contraction,improve the bowel condition and symptoms in the treatment of functional constipation in the elderly.

关 键 词：西沙必利 胆石通胶囊 老年人功能性便秘 

分 类 号：R574.62[医药卫生—消化系统]