107例动脉瘤性蛛网膜下腔出血患者预后的多因素分析  

Clinical characteristics and outcome analysis of 107 patients with aneurysmal subarachnoid hemorrhage

作　　者：王冠宇[1] 孙宇强[1] 谭泽士 刘晓光[1] 孙旭[1] 李新宇[1] 魏明海[1] 尹剑[1] 

机构地区：[1]大连医科大学附属第二医院神经外科,116023

出　　处：《临床神经外科杂志》2016年第2期136-140,共5页Journal of Clinical Neurosurgery

摘　　要：目的探讨动脉瘤性蛛网膜下腔出血(aSAH)患者的临床特点及其与预后的相关因素。方法回顾性分析大连医科大学附属第二医院神经外科2012年1月至2015年10月收治的107例SAH患者,根据GOS评分将病例分为预后良好组及不良组,采用单因素分析及对多因素Logistic回归分析,探讨上述各因素对预后的影响。结果全部107例患者经单因素分析显示,诱因、动脉瘤大小、Hunt-Hess评分、脑血管痉挛与患者预后明显相关(均P<0.05)。多因素Logistic回归分析显示,诱因(P=0.026)、动脉瘤大小(P=0.002)、Hunt-Hess评分(P=0.016)及脑血管痉挛(P=0.003)为影响a SAH患者预后的独立危险因素。结论 a SAH患者的发病诱因、动脉瘤大小、Hunt-Hess分级和脑血管痉挛是影响患者预后的危险因素。Objective To explore the clinical characteristics of patients with aneurysmal subarachnoid hemorrhage（ a SAH） and further clarify the relevance between the clinical factors and prognosis. Methods We retrospectively collected records of 107 cases of a SAH between January2012 to October 2015 at the Second Affiliated Hospital of Dalian Medical University. The cases were divided into two groups based on the GOS prognostic score： good prognosis group and poor prognosis group. All factors were processed by a mentioned above variable by a single factor and multivariate Logistic regression analysis,respectively. Results The single factor analysis showed that incentives,size of aneurysms,Hunt-Hess classification and cerebralvascular spasm were correlated with the prognosis of a SAH. Multiariable Logistic regression analysis showed the presence of incentives（ P =0. 026）,size of aneurysms（ P = 0. 002）,Hunt-Hess grading（ P = 0. 016） and cerebralvascular spasm（ P= 0. 003） were correlated with the prognosis of a SAH. Conclusions Incentives,size of aneurysms,Hunt-Hess classification and cerebralvascular spasm were independent risk factor of a SAH.

关 键 词：动脉瘤性蛛网膜下腔出血 预后 危险因素 多因素分析 

分 类 号：R739.41[医药卫生—肿瘤]