早期无创动脉硬化检测的临床应用研究  

Clinical application of early noninvasive detection on atherosclerosis

作　　者：赵中 陈文智 罗克 沈小平 郑建国 谭倩凡 

机构地区：[1]广东省罗定市人民医院预防保健科体检中心,广东罗定527200 [2]广东省罗定市人民医院预防保健科体检中心急诊科,广东罗定527200

出　　处：《中国当代医药》2016年第13期43-46,共4页China Modern Medicine

基　　金：广东省云浮市科技计划项目(WS1325)

摘　　要：目的探讨早期无创动脉硬化检测的临床应用价值。方法选取我院诊断的单纯高血压患者200例,分为对照组和观察组,各100例,两组均进行踝-臂脉搏波传导速度、踝臂指数、心踝血管指数、颈动脉内中膜厚度检查及常规内科体格检查。对观察组ba PWV、ABI、CAVI、IMT数值进行个体化分析并给予治疗;对照组仅给予常规内科治疗。观察比较两组血压病治疗率及控制率;治疗24个月后ba PWV、CAVI、IMT、动脉硬化及其相关性心脑血管疾病的发生率。结果观察组患者高血压病治疗率及控制率明显高于对照组(P<0.05),治疗24个月后观察组ba PWV,CAVI,IMT均明显低于对照组,动脉硬化及其相关性心脑血管疾病的发生率明显低于对照组(P<0.05)。结论基于早期无创动脉硬化检测指导下的临床诊疗可以明显提高高血压病患者的治疗率及控制率,改善ba PWV、ABI、CAVI和IMT,大幅度减少动脉硬化及相关的心脑血管疾病的发生。早期无创动脉硬化检测,对于加强动脉硬化疾病早期筛查、提高动脉硬化性疾病的防治水平具有重要意义。Objective To explore the clinical application value of early noninvasive detection on atherosclerosis. Meth- ods 200 patients with simple hypertension diagnosed in our hospital were selected and divided into control group and observation group,100 cases in each group.Patients in both groups were given examination of brachial-ankle pulse wave velocity （baPWV）,ankle-brachial index （ABI）,cardio-ankle vascular index （CAVI）,and intima-media thickness （IMT）,and routine physical examination.Patients in observation group were given individual analysis and treatment based on values of baPWV,ABI,CAVI and IMT,while patients in control group were only given routine medical treatment.Cure rate and control rate of blood pressure diseases were observed and compared,as well as baPWV,ABI,CAVI,IMT, and incidences of arteriosclerosis and relevant cardiovascular and cerebrovascular diseases after 24 months of treatment. Results The cure rate and control rate of hypertensive disease were significantly higher in the observation group than that of control group （P〈0.05）.BaPWV,ABI,CAVI and IMT were significantly lower in the observation group than that of control group, so as the incidences of arteriosclerosis and relevant cardiovascular and cerebrovascular diseases after 24 months of treatment （P〈0.05）. Conclusion Clinical treatment under guidance of early noninvasive detection of atherosclerosis can significantly enhance the cure rate and control rate in patients with hypertension,improve baPWV,ABI,CAVI and IMT, and evidently reduce the incidences of arteriosclerosis and relevant cardiovascular and cerebrovascular diseases.Early noninvasive detection of atherosclerosis has important significance in early screening of atherosclerosis and improve- ment of the prevention and control of atherosclerosis diseases.

关 键 词：动脉硬化 踝臂脉搏波传导速度 踝臂指数 心踝血管指数 颈动脉内中膜厚度 

分 类 号：R743.1[医药卫生—神经病学与精神病学]