富血小板血浆促进骨折愈合机制及研究进展  

The Mechanism and Research Progress of Platelet Rich Plasma in Promoting Fracture Healing

作　　者：赫兰学[1] 马震卓 丁雪峰[3] 李建杰[3] 

机构地区：[1]吉林市中心医院脊柱外科,吉林吉林132001 [2]吉化集团公司总医院放射科,吉林吉林132021 [3]吉化集团公司总医院检验科,吉林吉林132021

出　　处：《中国继续医学教育》2016年第11期77-78,共2页China Continuing Medical Education

摘　　要：目的探讨富血小板血浆(PRP)促进骨折愈合机制及研究进展。方法查阅国内外相关PRP制备、生长因子作用机制及促进骨愈合应用的相关文献,并进行回顾和综合分析。结果 PRP中所富含的各种生长因子之间可产生一定的协同,在骨折愈合早期发挥重要作用。结论 PRP对骨折愈合发挥促进作用受多种因素影响,血小板脱颗粒释放多种生长因子协同作用促进骨折愈合。Objective To study mechanism and research progress of the platelet rich plasma（PRP） for promoting fracture healing. Methods To review relevant literatures on PRP preparation, growth factors and promoting bone healing in domestic and overseas, And to carry on the review and the synthesis analysis. Results The PRP which contains a variety of growth factors can produce a certain synergy and play an important role in the early fracture healing. Conclusion The PRP which play a promoting role in fracture healing is influenced by many factors, the platelet degranulation release a variety of growth factors, which produce synergy for promoting fracture healing.

关 键 词：富血小板血浆 生长因子 骨修复 

分 类 号：R78[医药卫生—口腔医学]