抑郁症伴焦虑症状的影响因素分析  

Influencing factors of anxiety symptoms in patients with depression

作　　者：何小婷[1] 孙宁[1] 杜巧荣[1] 杨春霞[1] 刘志芬[1] 王彦芳[1] 李素萍[1] 张克让[1] 

机构地区：[1]山西医科大学第一医院精神科,太原030001

出　　处：《中国神经精神疾病杂志》2016年第4期206-210,共5页Chinese Journal of Nervous and Mental Diseases

基　　金：国家自然科学基金面上项目(编号:81171290;81471379);山西省高等学校科技创新项目(编号:2013119)

摘　　要：目的探讨抑郁症患者伴焦虑症状的发生情况,并从社会心理因素方面分析抑郁症伴焦虑症状的影响因素。方法采用汉密尔顿抑郁量表（Hamilton depression rating scale,HAMD）、汉密尔顿焦虑量表（Hamilton anxiety rating scale,HAMA）、艾森克人格问卷（Eysenck personality questionnaire,EPQ）、生活事件量表（life event scale,LES）、特质应对方式问卷（trait coping style questionnaire,TCSQ）、社会支持问卷（social support scale,SSS）对729例抑郁症患者进行评估,根据HAMA得分将患者分为不伴焦虑症状组（HAMA〈7分）和伴焦虑症状组（HAMA〉14分）,比较两组社会心理因素,并分析抑郁症伴焦虑症状的影响因素。结果抑郁症患者中焦虑症状（HAMA〉14分）的发生率为58.85%（429/729）,16.32%（119/729）肯定不伴焦虑症状（HAMA〈7分）。伴焦虑症状组神经质、精神质、负性生活事件、消极应对方式的得分高于不伴焦虑症状组（P〈0.001）;外倾性的得分低于不伴焦虑症状组（P=0.010）。抑郁程度（OR=9.255,95%CI：4.726~18.127）、神经质（OR=1.595,95%CI：1.197~2.125）、负性生活事件（OR=1.009,95%CI：1.001~1.017）、消极应对方式（OR=1.046,95%CI：1.013~1.080）均是抑郁症患者伴焦虑症状的危险因素（P〈0.05）。结论抑郁症患者焦虑症状的发生率高。抑郁症状严重、高神经质水平、经历更多负性生活事件、倾向于采用消极应对方式的抑郁症患者更有可能伴焦虑症状。Objective To investigate the status of depression with anxiety symptoms, and analyze the influencing factors of anxiety symptoms from demographic data and social psychological factors.MethodsHamilton depression rating scale（HAMD）, Hamilton anxiety rating scale（HAMA）, Eysenck personality questionnaire（EPQ）, life event scale（LES）, trait coping style questionnaire（TCSQ） and social support scale（SSS） were used to evaluate 729 patients with depression. According to HAMA scores, patients were divided into non anxiety symptoms group（HAMA7） and anxiety symptoms group（HAMA〉14）. Social psychological factors were compared between two groups, and the influencing factors of anxiety symptoms were analyzed.ResultsThe incidence of anxiety symptoms in depression was 58.85%（429/729）, and 119 cases（16.32%） were certainly without anxiety symptoms. Compared with the group without anxiety symptoms, the anxiety symptoms group had higher scores on neuroticism, psychoticism, negative life events and negative coping style（P〈0.001）, but lower scores on introversion and extroversion（P=0.010）. Degree of depression（OR=9.255, 95%CI： 4.726～18.127）, neuroticism（OR=1.595, 95%CI： 1.197～2.125）, negative life events（OR=1.009, 95%CI： 1.001～1.017）and negative coping style（OR=1.046, 95%CI： 1.013～1.080） were the risk factors of anxiety symptoms（P〈0.05）.ConclusionThe incidence of anxiety symptoms in patients with depression is high. Patients with higher degree of depressionand typical neurotic personality experiencing more negative life events and those with tendency to adopt negative coping style are more susceptible to anxiety symptoms.

关 键 词：抑郁症 焦虑症状 影响因素 回归分析 

分 类 号：R749.4[医药卫生—神经病学与精神病学]