近端胃切除与全胃切除在治疗近端胃癌中的疗效比较  

Comparison of the Efficacy of Proximal Gastrectomy and Total Gastrectomy in Treatment of Proximal Gastric Cancer

作　　者：孙虎[1,2] 范发明[1] 陶国泉 王静松[1] 黄建军[1] 

机构地区：[1]淮安市第一人民医院分院普外科,江苏淮安223001 [2]南京医科大学临床医学院,江苏南京210029 [3]淮安市第一人民医院普外科,江苏淮安223300

出　　处：《现代生物医学进展》2016年第15期2914-2917,共4页Progress in Modern Biomedicine

基　　金：江苏省科技成果转化专项资金项目(BA2011098)

摘　　要：目的:观察近端胃切除和全胃切除对近端胃癌的疗效。方法:比较28例患有早期近端胃癌接受近端胃切除28例患者与100例患有早期近端胃癌接受全胃切除的患者,观察近端胃切除是否优于全胃切除。结果:两种治疗方法手术时间、术后并发症(包括吻合口瘘)没有差异。两组患者胃切除后的代谢变化结果相似,体重,血清血红蛋白以及血清总蛋白浓度变化相近。近端胃切除后腹泻(32%)和胃食管返流(28%)最为常见,而全胃切除后餐后腹胀(21%)最为常见。二者的术后5年生存率没有明显差别。结论:近端胃切除不会由于残余胃的生理优势而优于全胃切除术。Objective： To observe the effect of proximal gastrectomy and total gastrectomy resection in treatment of proximal gastric cancer. Methods： In this observation, we selected 28 cases of primary proximal gastric cancer patients who underwent proximal gastric resection and 100 cases of primary proximal gastric cancer patients who underwent total gastrectomy. Analyze and compare the effects of proximal gastric resection and total gastrectomy. Results： There was no difference in operation time and postoperative complications（including anastomotic leakage） between two kinds of treatment methods. The metabolic changes of the two groups after gastrectomy were similar, and so were the changes of bodyweight, serum hemoglobin and serum total protein concentrations. Diarrhea（32%） and gastroesophageal reflux（28%） were the most common adverse events after proximal gastrectomy, but abdominal distension（21%） was the most common adverse event after total gastrectomy. There was no significant difference in the 5-year survival rate between two groups.Conclusion： Though proximal gastrectomy has the residual stomach physiological dominance, it had no better effect than total gastrectomy for primary proximal gastric cancer patients.

关 键 词：胃癌 全胃切除 代谢 

分 类 号：R735.2[医药卫生—肿瘤]