宫颈癌术后调强放疗与普通放疗对骨盆的影响  

Damage of Intensity-Modulated Radiation Therapy and Conventional Radiation Therapy after Operation to Pelvis of Patients with Cervical Cancer

作　　者：蔡海莹 柯佳捷 张摇威 谢扬[2] 

机构地区：[1]潮州市潮安区人民医院,广东潮州515638 [2]汕头大学医学院第二附属医院,广东汕头515041

出　　处：《现代医院》2016年第5期656-657,共2页Modern Hospitals

基　　金：广东省科技计划项目(编号:2012B031800442)

摘　　要：目的分析比较调强放疗（Intensity—modulatedRadiationTherapy，IMRT）与普通放疗（radiationther—apy，RT）在宫颈癌术后治疗对骨盆正常组织的影响。方法收集2010年1月～2015年12月在医院行手术治疗后接受IMRT的109名宫颈癌患者临床资料，与既往在医院接受RT的109名宫颈癌术后患者临床资料进行对比，回顾分析治疗前和治疗后的CT扫描结果，比较IMRT与RT对骨盆的影响。结果IMRT组中，4例出现骨折（随访中位时间26．0个月），RT组出现18例骨盆并发症，其中12例骨折，2例股骨头坏死，4例骨髓炎（随访中位时间31．0个月），两组数据具有统计学差异（P=0．01）。结论IMRT出现骨盆并发症的风险明显小于RT。Objective To analyze and compare the damage of intensity - modulated radiation therapy （IMRT） and conventional radiation therapy after operation to pelvis of patients with cervical cancer. Methods The clinical data of 109 patients treated with IMRT after cervical cancer operation were collected and reviewed in comparison with the data of another 109 patients previously treated with RT. Pretreatment and post - treatment computed tomography scans were reviewed so as to compare the influence of IMRT and RT on the pelvis. Results In the IMRT group, 4 of 109 patients developed sacral frac- tures （The median follow - up time was 26 months）. In the conventional RT group, 18 came out with pelvic girdle complica- tions, with 12 cases of fractures, 2 osteonecrosis, and 4 osteomyelitis （The median follow - up time was 31 months）. These data were significantly different （ P = 0. 01 ）. Conclusion Significantly, the patients treated with intensity - modulated radi- ation therapy have a lower risk of pelvic girdle complications than conventional RT.

关 键 词：宫颈癌 调强放疗 普通放疗 并发症 

分 类 号：R737.33[医药卫生—肿瘤]