Alzheimer病胼胝体萎缩的MRI定量研究  

MRI study on corpus callosum atrophy in alzheimer disease

作　　者：张雪宁[1] 陈希颖[1] 

机构地区：[1]天津医科大学第二医院放射科,天津300211

出　　处：《天津医科大学学报》2002年第3期289-290,共2页Journal of Tianjin Medical University

基　　金：天津市自然科学基金项目资助(编号003606511)

摘　　要：目的 :评价胼胝体面积测量对诊断Alzheimer病(Alzheimerdisease,AD)的价值。方法 :14名AD患者和20名年龄、性别、受教育程度相匹配的正常对照 ,进行MRI扫描并全部行简易精神状态量表 (MMSE)检查。结果 :AD组胼胝体面积区域性减少 ,胼胝体萎缩与AD的认知功能损害显著相关。结论Objective: To evaluate the value between the corpus callosum atrophy measurement of MR imaging and cognitive function disturbance.methods:Fourteen patients with Alzheimer disease( AD) and 20 matched normal controls were studied in MRI and mini-mental state examination(MMSE) were studied. Results: Total callosal size was significantly reduced. Significant correlates were observed between the areas of callosal atrophy and MMSE. Conclusion: The measurements of callosal areas can help diagnosis of AD.

关 键 词：诊断 Alzyheimer病 胼胝体萎缩 MRI 

分 类 号：R749.16[医药卫生—神经病学与精神病学]