二茂铁键合硅胶液相色谱固定相的制备与评价  

Preparation and Characterization of Ferrocene-bonded Silica Stationary Phase for High Performance Liquid Chromatograph

作　　者：余小波[1] 胡志雄[1,2] 张维农[1,2] 贺军波[1,2] 齐玉堂[1] 

机构地区：[1]武汉轻工大学食品科学与工程学院,湖北武汉430023 [2]农产品加工湖北省协同创新中心,湖北武汉430023

出　　处：《山东化工》2016年第10期1-4,8,共5页Shandong Chemical Industry

基　　金：国家自然科学基金项目(31371783);国家粮食公益性行业科研专项(201313007);湖北省自然科学基金项目(2014CFB885)

摘　　要：基于硫醇-烯点击化学反应,以γ-巯丙基三甲氧基硅烷为偶联剂合成了一种新型二茂铁键合液相色谱固定相(FSP),并采用红外光谱、元素分析对该色谱固定相的进行了表征,以苯及其4种同系物、4种酚类化合物和6种多环芳烃为溶质,甲醇/水为流动相,初步考察了该新型固定相的基本色谱性能,表明该固定相对化合物的选择性较好,峰形对称,具有显著的反相特征。A novel ferrocene- bonded silica stationary phase（ FSP） for reversed- phase liquid chromatography was prepared based on thiol- ene click chemistry,using 3- mercaptopropyl trimethoxysilane（ KH- 590） as the coupling reagent. The characterization of the prepared packing was carried out with Fourier transform infrared spectroscopy（ FT-IR） and elemental analysis（ ES）. The chromatographic evaluations were carried out by testing with some alkylbenzene homologues,four phenols and six PAHs using methanol- water as a binary mobile phase. According to chromatographic data,it can be concluded that FSP has excellent selectivity,stationary peak shapes and significant reversed- phase chromatographic property.

关 键 词：二茂铁 点击化学 高效液相色谱 固定相 

分 类 号：O657.72[理学—分析化学]