消化性溃疡规范化治疗模式的应用和价值  

Value of standardized treatment mode for peptic ulcer

作　　者：江永平[1] 蒋宁[1] 张勇[1] 李明娟[1] 杨佐南 

机构地区：[1]浙江省嘉善县第一人民医院消化科内镜中心,浙江省嘉兴市314100

出　　处：《世界华人消化杂志》2016年第13期2081-2086,共6页World Chinese Journal of Digestology

基　　金：浙江省第一批基层卫生适宜技术示范基地(嘉善县基地)基金资助子项目;2015年嘉兴市第一批科技计划基金资助项目(自主设计研发专项);No.2015C23035;2014年嘉善县科技局科技计划基金资助项目;No.2014A45~~

摘　　要：目的:评价消化性溃疡规范化治疗模式效果.方法:将消化性溃疡患者189例分成规范组(n=96)与对照组(n=93),规范组实施规范化治疗模式,对照组接受既往常规诊疗模式,比较两组患者治疗后幽门螺杆菌(Helicobacter pylori,H.pylori)根除、溃疡愈合、溃疡复发情况和患者依从性、满意度评分、疾病知识知晓率等指标的差异.结果:规范组H.pylori根除率和溃疡愈合率分别高于对照组(84.21%vs 58.89%)、(42.11%vs 28.89%),组间差异有统计学意义(P<0.05),规范组溃疡复发率低于对照组(12.63%vs 17.78%),但组间差异无统计学意义(P>0.05).185例患者的总体服药依从性平均得分6.69分±1.35分,其中规范组得分高于对照组得分(7.22分±1.34分vs 6.17分±1.37分),规范组满意度评分高于对照组满意度评分(4.31分±0.99分vs 3.06分±1.26分,规范组疾病知识知晓率明显高于对照组(70.53%vs 46.67%),规范组患者依从性、满意度和疾病知识知晓率均高于对照组,组间差异均有统计学意义(P<0.05).结论:消化性溃疡实施规范化治疗模式能有效提高患者H.pylori根除成功率、溃疡愈合率、疾病知识知晓率、用药依从性和患者的治疗满意度,是当前消化性溃疡防治的有效策略,适宜在临床工作中推广.AIM：To evaluate the effect of standardized treatment mode for peptic ulcer.METHODS：One hundred and eighty-nine patients with peptic ulcer were divided into a standardized treatment group（n = 96） and a control group（n = 93）.The standardized treatment group received standardized treatment regimen,and the control group was treated with conventional therapy.After treatment,the two groups were compared regarding Helicobacter pylori（H.pylori） eradication,ulcer healing,ulcer recurrence,patient compliance,satisfaction score,and rate of disease knowledge awareness.RESULTS：The H.pylori eradication rate and ulcer cure rate were significantly higher in the standardized treatment group than in the control group（84.21% vs 58.89%,42.11% vs28.89%,P〈0.05）.The rate of ulcer recurrence did not differ significantly between the standardized treatment group and the control group（12.63% vs 17.78%,P〈0.05）.Average score of therapeutic compliance in the 185 patients was 6.69 ± 1.35,among which the score was significantly lower in the standardized treatment group than in the control group（7.22 ±1.34 vs 6.17 ± 1.37,P〈0.05）.The satisfaction degree was also significantly higher in the standardized treatment group than in the control group（4.31 ± 0.99 vs 3.06 ± 1.26,P〈0.05）.The standardized treatment group presented higher rate of disease knowledge awareness than the control group（70.53% vs 46.67%,P〈0.05）.CONCLUSION：The standardized treatment mode for peptic ulcer could effectively increase the eradication rate of H.pylori,ulcer healing rate,patient＇s knowledge about the disease,medication compliance and patient treatment satisfaction,representing an effective strategy for prevention and treatment of peptic ulcer.

关 键 词：消化性溃疡 规范化治疗 治疗模式 

分 类 号：R573.1[医药卫生—消化系统]