免疫抑制剂治疗顽固性葡萄膜炎的临床效果  

Clinical effect of immunity inhibitor in treating stubborn intermediate uveitis

作　　者：房强 任大元 

机构地区：[1]解放军第一四八医院眼科,山东淄博255300

出　　处：《中国当代医药》2016年第14期78-80,共3页China Modern Medicine

摘　　要：目的探讨采用免疫抑制剂治疗顽固性葡萄膜炎的临床效果。方法随机抽取2013年1月-2015年12月我院眼科收治的100例顽固性葡萄膜炎患者作为此次研究的对象,采取抛掷硬币法将患者分为对照组和观察组,每组50例。对照组给予糖皮质激素药物治疗,观察组在糖皮质激素药物治疗的基础上加用免疫抑制剂治疗。比较两组患者的临床总有效率、视力恢复时间、用药总时间以及不良反应发生率。结果观察组的临床总有效率为92%,明显高于对照组的76%,差异有统计学意义（P〈0.05）。与对照组比较,观察组的视力恢复时间、用药总时间均明显缩短,差异有统计学意义（P〈0.05）。观察组的不良反应发生率为2%,明显低于对照组的16%,差异有统计学意义（P〈0.05）。结论在顽固性葡萄膜炎患者的临床治疗中应用免疫抑制剂,具有显著的临床效果。Objective To explore the clinical effect of using immunity inhibitor in treating stubborn intermediate uveitis. Methods 100 stubborn intermediate uveitis patients from January 2013 to December 2015 in ophtalmology department of our hospital were randomly selected as study object for this research.Patients were divided into control group and observation group by using throw coin method,and each group was 50 cases.Patients in control group were used glucocorticoid,and patients in observation group were used immunity inhibitor on the basis of glucocorticoid.The clinical total effective rate,vision recovery time,the total time of drug use and the incidence rate of adverse effects in two groups were compared. Results The clinical total effective rate in observation group was 92%,which was obvious higher than that was 76% in control group（P〈0.05）.Compared with control group,the vision recovery time and the total time of drug use in observation group were shorten obviously（P〈0.05）.The incidence rate of adverse effects in observation groups was 2%,which was obvious lower than that was 16% in control group（P〈0.05）. Conclusion Using immunity inhibitor in treating stubborn intermediate uveitis has obvious clinical effect.

关 键 词：免疫抑制剂 顽固性葡萄膜炎 糖皮质激素 

分 类 号：R773[医药卫生—眼科]